Project Grant R01DK147446
- Federal Project Grant Award Summary The University of Minnesota, through its Office of Sponsored Projects Administration, received a $4.5 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, effective September 5, 2025, through August 31, 2028, funds research to develop engineered regulatory T cells (Tregs) as a therapeutic intervention for...
- Federal Project Grant Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $153,500 to the University of Florida Division of Sponsored Research on May 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for a two-year project concluding April 30, 2028. The research project, titled "Assessment of Thymic Output in the Context of Genetics, Environmental Exposures, and Progression to Type 1 Diabetes,"...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a Project Grant of $248,975 to University of Colorado-Denver under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) on May 15, 2026, with final completion scheduled for April 30, 2029. The research project investigates pancreatic beta-cell glucose toxicity and messenger RNA (mRNA) translation dysfunction in the context of type 1 diabetes...
- Federal Grant Award Summary The Beckman Research Institute of The City of Hope received an $8.4 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for a three-year period from May 1, 2026, through April 30, 2029. The award funds research investigating circulating extracellular vesicles (CEVs) as biomarkers for early detection and pathogenesis of human Type 1...
- Federal Grant Award Summary The Scripps Research Institute received a $1.6 million Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded August 15, 2025, with completion targeted for June 30, 2029. The research initiative focuses on elucidating the initiation of anti-islet autoimmunity and the regulation of major histocompatibility complex (MHC) Class II...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $451,000 Project Grant to The Regents of the University of California, San Francisco on September 5, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports a two-year research initiative (completion by August 31, 2027) investigating the role of microRNAs in adipose tissue dysfunction among people with HIV (PWH) who...
- Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded the University of Florida a $754,682 Project Grant effective May 1, 2026, through April 30, 2030, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This research initiative addresses beta cell dysfunction in Type 1 Diabetes (T1D) by investigating the metabolic and immunological mechanisms underlying disease progression. The project employs two...
- Federal Grant Award Summary Florida State University received a $2.78M Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 1, 2025, through August 31, 2029. The award supports fundamental research to elucidate the molecular mechanisms by which pancreatic beta cells transition from adaptive responses to maladaptive dysfunction under...
- Federal Project Grant Award Summary The University of Miami's Office of Research Administration – School of Medicine Division received a $537,250 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded June 1, 2026, with completion targeted for March 31, 2029. This research project investigates the neuronal entero-pancreatic circuit's role in glucose...
- Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $6.62 million in Project Grant funding under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Virginia, with an award date of May 1, 2026, and completion scheduled for April 30, 2029. The project, "Dynamic Regulation of Alternative Splicing in the Initiation and Progression of Islet Autoimmunity in the Environmental Determinants of...
The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of South Florida a $4.64 million Project Grant (CFDA 93.847: Diabetes, Digestive, and Kidney Diseases Extramural Research) effective July 15, 2026, through June 30, 2029. This research project will identify and validate circulating microRNA (miRNA) biomarkers for predicting Type 1 Diabetes (T1D) progression using longitudinal plasma samples from the TEDDY (The Environmental Determinants of Diabetes in the Young) study, a natural history study following genetically at-risk subjects from birth through age 15. The project will measure miRNA levels to discover and validate miRNA signatures associated with disease progression and assess miRNA responses during oral glucose tolerance tests to identify functional biomarkers linked to beta cell dysfunction. The deliverables from this award include validated plasma miRNA biomarker signatures at different disease progression stages, functional data characterizing miRNA responses to metabolic stimulation, and scientific publications reporting findings that will inform improved screening and primary prevention strategies for T1D. By leveraging existing longitudinal biosamples and clinical data from the TEDDY cohort, the research aims to translate miRNA profiling into practical predictive tools for identifying individuals at risk of T1D, thereby advancing early intervention and prevention efforts in pediatric diabetes.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.6m | 7/16/26 |