Project Grant R01DK144547
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Alabama at Birmingham $650,509 on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate the myeloid ferritin–CXCL3 axis as a driver of acute kidney injury (AKI) progression to chronic kidney disease. The research leverages novel transgenic mice with targeted deletion of ferritin genes in myeloid cells to determine whether myeloid...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the Veterans Medical Research Foundation of San Diego $383,098 on September 2, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The recipient will conduct research into kidney tubule dysfunction in APOL1-associated chronic kidney disease, with focus on developing and validating tubular biomarkers that capture kidney functions—nutrient reabsorption and toxin...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded The Trustees of Columbia University in the City of New York $123,375 on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct structure-guided research aimed at preventing polymyxin-induced acute kidney injury. The project will characterize the interaction between polymyxin B and the endocytic receptor LRP2/megalin using cross-linking mass spectrometry...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Weill Medical College of Cornell University $1,433,882 on September 15, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to characterize hospital-to-skilled nursing facility (SNF) care transitions for patients with end-stage kidney disease and examine associations between transition patterns and clinical outcomes. The research project, R01DK144679, runs through August...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded New York University $872,273 on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify modifiable process delays in deceased donor kidney allocation through process mining analysis. The project applies process mining methodology to discover actual kidney placement workflows from data logs at multiple organ procurement organizations (OPOs). The research...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded New York University $412,992 on May 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct the Surveillance of Nutritional Risk for Acute Kidney Injury in Critically Ill Kids (SNACK) study. The study evaluates whether poor baseline nutritional status is a modifiable risk factor for acute kidney injury in pediatric intensive care unit patients. The research...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Washington $192,763 on March 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), a Project Grant supporting basic and clinical biomedical research that improves understanding of disease mechanisms and leads to improved prevention, diagnosis, and treatment. The award funds a prospective nested cohort study investigating mechanisms of kidney...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $1,527,305 to The Research Foundation For The State University Of New York (operating as Stony Brook University) on August 21, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to conduct research on C-terminal binding protein 2 (CTBP2) as a therapeutic target in acute kidney injury. The research identifies CTBP2, a redox-sensitive, NAD/NADH-dependent transcriptional...
- The National Institute of Diabetes and Digestive and Kidney Diseases, an institute within the Department of Health and Human Services National Institutes of Health, awarded the Regents of the University of Michigan $690,854 on February 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research to identify molecular and genetic mechanisms that determine and maintain kidney epithelial cell states in normal physiology and in...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Purdue University $120,937 on July 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop bioinspired, multi-antioxidant nanomedicine for treating acute kidney injury. The award funds synthesis and evaluation of a library of sub-5 nanometer chalcogen-phenolic nanoparticles (CPNP) designed to neutralize reactive oxygen species in kidney tissue while accumulating...
The National Institute of Diabetes and Digestive and Kidney Diseases, part of the Department of Health and Human Services National Institutes of Health, awarded Weill Medical College of Cornell University $829,125 on September 1, 2026, to define and prevent iron-induced tubular injury in chronic kidney disease under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research develops urinary proximal tubular cell assays using fluorescent probes to enable non-invasive quantification of tubular iron status in mice and humans. The recipient will map how chronic kidney disease alters tubular iron handling across glomerular and non-glomerular models, test tubular-specific ferroportin knockouts, and link disease and protein leak to tubular iron toxicity through analysis of urinary cells in patients enrolled in the recipient's chronic kidney disease registry. The work also evaluates how iron formulation and delivery route determine the fraction of labile iron reaching tubular cells, and tests novel iron-shuttling therapies for reversible iron removal. Work is performed in New York, New York. The period of performance extends from September 1, 2026, through July 31, 2031. The award is a Project Grant, an assistance type supporting investigator-initiated research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $829.1k | 8/19/26 |