Project Grant R01DK143536
- This $451,000 Project Grant was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund research to investigate the role of microRNAs in adipose tissue from people with HIV who develop type 2 diabetes. The project aims to evaluate microRNA expression in adipose tissue and explore whether circulating microRNAs in plasma could serve as biomarkers of risk...
- This $1,554,672 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) aims to define the molecular mechanisms underlying gut inflammation and barrier dysfunction in people living with HIV. The grant supports research led by The Washington University in Missouri to establish a novel humanized mouse model that can faithfully recapitulate HIV infection in...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $773,112 Project Grant to Rockefeller University on September 5, 2025 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate the mechanisms of transcriptional control in adipocyte formation and function through nuclear receptor coactivators. The research aims to provide a better understanding of dysregulation in energy storage...
- This $780,853 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) aims to investigate the impact of a glucagon-like peptide-1 receptor agonist on simian immunodeficiency virus (SIV)/human immunodeficiency virus (HIV) pathogenesis and antiretroviral therapy (ART) administration in people living with HIV. The project, to be conducted by the University of Pittsburgh from April 2025 through March 2030, will assess changes in T-cell and...
- This Project Grant award of $248,915 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to unravel the role of epigenetics and cytokines in type 2 diabetes among African-ancestry populations in the U.S. and Europe. The research aims to identify causal associations between DNA methylation, circulating cytokines, and diabetes risk in these populations...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), awarded a $133,333 Project Grant to Yale University to study the mechanisms underlying the myeloid bias in aged hematopoietic stem and progenitor cells (HSPCs). The research aims to correct this myeloid bias by preventing the turnover of the linker histone H1.0, which could have implications for addressing diverse...
- This federal Project Grant award for $829,985 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research by the University of Virginia to develop new Drosophila, mouse, and human podocyte models to study the interaction between HIV, APOL1 risk alleles (G1 and G2), and chronic kidney disease in people living with HIV. Key objectives include...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $762,556 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to Aurora Health Care, Inc. The award supports the development of a novel, semi-automated self-monitoring feedback system for health promotion in community settings. The project aims to optimize the efficacy of feedback messages related to dietary intake, physical activity, and weight...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, awarded a $728,801 Project Grant to the Regents of the University of Michigan under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds a 5-year project to test a novel weight navigation program aimed at overcoming barriers to obesity treatment in primary care settings. The project seeks to improve utilization of effective...
- This federal Project Grant award of $159,775.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to elucidate the regulation of choline metabolism under obese conditions and its impact on metabolic health. Key activities include in vivo flux analysis to map the fate of choline in the livers of control and choline carrier knockout...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $1,778,953 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Regents of the University of Minnesota. The award, with a start date of September 16, 2025 and a completion date of June 30, 2029, will support research on the dynamics of the HIV reservoir and its association with metabolic complications of HIV infection in individuals receiving continuous antiretroviral therapy and maintaining viral suppression. The project aims to explore the relationship between the persistence of HIV RNA+ cells and chronic immune activation, which may contribute to the development of comorbidities such as obesity, diabetes, and cardiovascular disease in people living with HIV.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.8m | 9/15/25 |