Project Grant R01DK143032
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Icahn School of Medicine at Mount Sinai a Project Grant totaling $645,617 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, effective July 1, 2025, through April 30, 2030, funds a five-year research initiative to understand hematopoietic stem cell (HSC) dysfunction in refractory Crohn's disease. The research addresses a critical...
- Federal Project Grant Award Summary Icahn School of Medicine at Mount Sinai received a Project Grant award of $683,660 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, effective February 15, 2026, through December 31, 2029, supports mechanistic research investigating the role of the EYA1 gene as a novel regulator of HIV-associated end-stage kidney disease...
- Federal Grant Award Summary Icahn School of Medicine at Mount Sinai received a $462,454 Project Grant awarded on August 8, 2025, under the Trans-NIH Research Support program (CFDA 93.310) from the National Institutes of Health Office of the Director. The project, "Characterizing DNA Methylation Dynamics in Trisomy 21-Associated Hematopoiesis and Leukemia," will be completed by June 30, 2027, and delivers advanced genomic research services focused on understanding epigenetic...
- Federal Project Grant Award Summary Albert Einstein College of Medicine received a $829,319 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective February 1, 2026, through November 30, 2030. The research project will investigate the collaborating factors driving DDX41 (ATPASE Dead-Box Helicase 41) mutant pathology in myelodysplastic syndromes...
- Federal Grant Award Summary Icahn School of Medicine at Mount Sinai received a $132,677 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 5, 2025, with a completion date of July 31, 2027. This grant supports research to map inflammatory bowel disease (IBD) variants to genes and functional phenotypes in human macrophages. The research employs large-scale CRISPRi perturb-seq...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Icahn School of Medicine at Mount Sinai a Project Grant of $169,000 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) effective September 5, 2025, with completion targeted for August 31, 2026. The research project, titled "Defining the Contributions of Amygdalar Circuits to the Metabolic Responses to Homeostatic Challenge," delivers...
- Federal Project Grant Award Summary Icahn School of Medicine at Mount Sinai received a $361,250 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 1, 2025, with completion scheduled for June 30, 2028. The award funds a Phase 2 randomized, placebo-controlled crossover clinical trial investigating atomoxetine, an existing...
- Federal Project Grant Award Summary New York University School of Medicine received a $830,401 project grant awarded September 15, 2025, with a completion date of July 31, 2030, from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research into fat and iron-corrected quantitative MRI T1 mapping technology for evaluating chronic liver disease,...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $253,500 Project Grant to Icahn School of Medicine at Mount Sinai on August 21, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds research through June 30, 2027, focused on advancing understanding of beta cell regenerative drug therapies for diabetes treatment. The research delivers longitudinal single-cell...
- Federal Project Grant Award Summary Icahn School of Medicine at Mount Sinai received a $507,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 7, 2025, with a completion date of July 31, 2030. This research grant supports the development and validation of metalloimmunotherapy—a novel immunotherapeutic approach leveraging metal ion interactions with immune system...
Icahn School of Medicine at Mount Sinai received a $871,028 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective March 1, 2026, with completion targeted for December 31, 2030. The award funds research to investigate iron trafficking mechanisms in myelodysplastic syndrome (MDS) erythropoiesis. Specifically, the research project examines how excess iron overload impairs red blood cell production in MDS patients and seeks to identify therapeutic targets to ameliorate ineffective erythropoiesis through modulation of iron trafficking and transferrin saturation regulation. The project advances fundamental understanding of iron metabolism in hematologic malignancy by conducting mechanistic studies on aberrant cellular iron sensing in MDS patient erythroblasts and evaluating the role of monoferric transferrin variants as regulatory nodes in erythropoietin responsiveness. The research deliverables include characterization of iron trafficking abnormalities in MDS and development of evidence-based approaches to improve hemoglobin production and reduce transfusional iron overload complications, potentially providing novel therapeutic strategies for a patient population with limited treatment options for ineffective erythropoiesis.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $871.0k | 2/18/26 |