Project Grant DP2AI192719
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $132,677 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai (ISMMS) to conduct research on mapping genetic variants associated with inflammatory bowel disease (IBD) to their target genes and functional effects in human macrophages. The project aims to elucidate the transcriptional consequences of IBD candidate genes in monocytes and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $929,500 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai (ISMMS) on July 23, 2025. The grant supports research to investigate the mechanism of action of different vaccine platforms, including mRNA-based and Newcastle Disease Virus (NDV)-based vaccines, in inducing long-lasting protective systemic and mucosal immune responses against...
- The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), awarded a Project Grant of $147,486.00 to the Icahn School of Medicine at Mount Sinai (ISMMS) in New York, NY. The grant, awarded on January 26, 2025, will support research to characterize the immune landscape and define the mechanisms of immune dysfunction in chronic hepacivirus infection, using the Norway rat hepacivirus (NRHV) as a model....
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $164,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Albany Medical College. The grant supports research to identify and characterize additional conformer-specific anti-I-A monoclonal antibodies (mAbs) to study the structure and function of MHC class II molecules, which are important for T cell-mediated immune responses. The research aims to address limitations in existing...
- The Icahn School of Medicine at Mount Sinai was awarded a $6,732,986 Cooperative Agreement from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to study the oral environment and its role in the development of food allergy. The project, titled "The Oral Environment in Food Allergy Development (ONEIDA)", aims to characterize the early-life trajectories of oral mucosal immunology, oral microbial communities, and...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $192,268 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai (ISMMS) to assess the effects of proposed HIV cure strategies in the gut-associated lymphoid tissue. This 5-year award, starting on August 26, 2025, aims to investigate the impact of HIV cure approaches on the viral reservoir located in the gut, as a large proportion of the...
- The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, awarded a $805,375 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai. The grant, awarded on November 20, 2024, supports a 5-year research project to elucidate the cellular tropism, receptor usage, and pathogenesis mechanisms of emerging bat-derived pararubulaviruses, which pose a potential global health...
- This Project Grant award of $797,735 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research CFDA program, aims to elucidate the innate and adaptive immune mechanisms governing neonatal immune responses and sterile inflammation in early life. The research project will utilize a novel mouse model of allergen-induced neonatal sterile inflammation to investigate heightened innate and adaptive immune responses in neonates compared to...
- This federal Project Grant award in the amount of $850,491.00 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai. The grant supports a research project to conduct an in-depth characterization of myeloid cells in human milk from both HIV-positive and HIV-negative donors. The goal is to investigate the potential role of these milk cells as...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $101,982 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) program to the University of Massachusetts Medical School (UMMS) to conduct research on the "Temporal Regulation of mRNA Biogenesis in Immune Responses." This 21-month project, running from May 2025 to February 2027, seeks to uncover mechanistic insights into the regulation and impact of stimulus-induced immune mRNA...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $507,000 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to the Icahn School of Medicine at Mount Sinai (ISMMS). The grant, awarded on August 7, 2025, aims to systematically investigate the interactions between metal ions and the immune system, and to develop specialized metal ion delivery systems to modulate immune responses for disease therapy. The overarching goal is to leverage the regulatory effects of metal ions on various immune pathways to activate or regulate immune responses, with a focus on addressing gut diseases like colon cancer and inflammatory bowel diseases. The award will support research activities at ISMMS over a project period lasting until July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $507.0k | 8/7/25 |