Project Grant R01DK141779
- This $2,060,811 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research on the role of activin type II receptor signaling in muscle hypertrophy, obesity, and weight loss. The research aims to understand how blocking the activin type II receptor can preserve lean muscle mass while maximizing fat loss during obesity treatment,...
- This $2,638,760.00 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research aims to investigate a novel mechanism involving the metabolite rhodoquinone (RQ) and its potential role in improving mitochondrial function and mitigating metabolic diseases caused by obesity. Specifically, the project will elucidate how the RQ/fumarate...
- This Project Grant award for $143,874 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research to identify mechanisms of resistance exercise training (RET) that enhance muscle insulin sensitivity and metabolism. The research, conducted by the Mayo Clinic, a renowned non-profit academic medical center, aims to measure the synthesis rates of individual muscle proteins in response to...
- This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), funded under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to develop a noninvasive method for earlier detection of skeletal muscle insulin resistance and dysfunction as a precursor to type 2 diabetes. The $389,621 award will support prospective ultrasound imaging of skeletal muscles, concurrent laboratory testing, and analysis of muscle...
- This $2,559,138 Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to define the mechanisms regulating adipose (fat) tissue metabolic memory and its role in rebound weight gain following obesity treatment. The project, led by researchers at the University of Pennsylvania, aims to: 1) determine the role of LYVE1+ macrophages in...
- This $854,803 federal Project Grant was awarded on June 13, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will fund the creation of a comprehensive, curated data repository for indirect calorimetry experiments in mice, which will capture critical data on factors influencing energy homeostasis, such as food intake, metabolic rate, and physical activity....
- This federal Project Grant award in the amount of $1,428,186.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts. The project aims to investigate the role of CYP4F enzymes in regulating N-acyl amino acid signaling in humans, which has implications for understanding the early...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health, awarded a $728,801 Project Grant to the Regents of the University of Michigan under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant funds a 5-year project to test a novel weight navigation program aimed at overcoming barriers to obesity treatment in primary care settings. The project seeks to improve utilization of effective...
- The University of Kansas Medical Center Research Institute, Inc. (KUMCRI) was awarded a $665,250 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant, effective September 1, 2025 through June 30, 2030, will establish a Nutrition Obesity Research Centers Research Resource Center (NORC-RRC) at KUMCRI. The NORC-RRC will consist of an Administrative Core,...
- This Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to understand the mechanisms by which glucocorticoid drugs induce insulin resistance and metabolic dysfunction in skeletal muscle. The $112,500 award, with a project period from September 1, 2024 to August 31, 2025, will be conducted by the Pennington Biomedical Research...
This $789,684 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund a study to examine the effects of anti-obesity medications, both with and without exercise, on changes in body composition including muscle mass. The study, to be conducted by the University of Kansas Medical Center Research Institute, Inc., will use the validated deuterated creatine dilution method to directly assess muscle mass, which has not been done in previous studies on these anti-obesity treatments. The results aim to provide important clinical insights on the impact of these medications and exercise interventions on preserving lean body mass and muscle during weight loss. The award period is from September 15, 2025 to August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $789.7k | 9/11/25 |