Project Grant R01DK140367
Award Date
7/10/24
Completion Date
6/30/29
Dollars Obligated
$1.5M
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Berkeley, CA 94720, USA
Similar Awards
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $243,590 to the University of Chicago to investigate the role of the protein BNIP3 in regulating lipid homeostasis in the liver. The goal is to define the mechanisms by which BNIP3 influences the accumulation of lipid droplets, which is a key factor in the development of non-alcoholic...
This $1,596,244 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) will fund research at Rutgers University to investigate the molecular mechanisms by which a high-fat diet suppresses calcium signaling in the liver. The proposed research aims to: 1) Identify how high-fat diet impairs calcium signaling in hepatocytes through the activation of novel protein kinase C isoforms,...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) provides $130,607 to the University of California, Los Angeles (UCLA) to investigate the role of peroxisomal PEX family proteins in hepatic bile acid and lipid metabolism. The research aims to dissect how the loss of PEX6 and PEX14 proteins impacts lipid homeostasis and inter-organelle crosstalk...
This $1,558,188 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) supports research to investigate how changes in transcription factor and heterochromatin states impact liver development, homeostasis, and regeneration. The primary awardee, The Trustees of the University of Pennsylvania, will use advanced in vivo imaging technologies and genetic...
This federal Project Grant award of $675,660.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award was granted to the Beth Israel Deaconess Medical Center, Inc. (Bidmc) to conduct research focused on understanding the regulation and requirements for coenzyme A (CoA) biosynthesis, and how dysregulation of CoA synthesis is related to metabolic diseases...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research into the role of the unfolded protein response (XBP1 pathway) in regulating bile acid metabolism during cholestatic liver disorders. The $1,170,271 award to Northwestern University, spanning from December 2024 to November 2028, aims to elucidate the mechanisms by which XBP1...
This federal Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research at the Pennington Biomedical Research Center to examine the role of the mitochondrial protein SLC25A25 in the onset and progression of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH)....
This $754,400 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research (CFDA 93.847) program. The funding will support research by The University of Texas Southwestern Medical Center (UT Southwestern) to identify adaptive genetic pathways and understand how mutant clones expand within chronically damaged liver tissues, with the goal of developing therapeutic approaches...
This $146,570 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to elucidate the cis-regulatory function of non-coding genetic variants associated with metabolic dysfunction-associated steatotic liver disease (MASLD). The research, led by The Trustees of the University of Pennsylvania, seeks to: Investigate the cis-regulatory activity of...
The federal Project Grant award R01DK140159, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the potential of a novel adipokine in resolving non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in animal models. The $469,235 award, with a start date of September 1, 2024, and an ultimate completion date of June 30,...