Project Grant R01DK138150
Award Date
9/6/24
Completion Date
6/30/28
Dollars Obligated
$582K
Federal Grant Program
93.847
Assistance Type
Project Grant
Place of Performance
Augusta, GA 30912, USA
Similar Awards
This federal Project Grant award of $117,000.00, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports a systems biology research project to identify gene regulatory networks related to the hypoxia-inducible factor 1-alpha (HIF1A) in the kidney cortex and medulla. The research aims to validate predicted transcription factor motifs, generate multiome data on...
This $199,922 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the role of iron homeostasis in kidney fibrosis and disease progression for chronic kidney disease (CKD). The award will be used by the Weill Medical College of Cornell University, the prime recipient, to conduct studies exploring the mechanisms by which...
This federal Project Grant award of $704,454.00 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research aimed at developing new therapies to limit renal ischemia-reperfusion injury and preserve renal function following kidney transplantation and other clinical scenarios. The principal investigators, Drs. Matthew Levine and Wayne Hancock, will explore the...
This $464,446 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to investigate the mechanisms of acute kidney injury associated with mechanical ventilation in critically ill patients. The project aims to: 1) identify the physical changes in glomerular function that lead to decreased kidney filtration during mechanical...
This $628,987.00 five-year Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) is supporting research to understand how increasing mitochondrial superoxide (O2-) dismutation in renal tubular cells can reduce cisplatin-induced kidney injury and promote repair. The key objectives are to: 1) determine how tubular mitochondrial O2- interactions with...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), through the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), has awarded a $548,830 Project Grant to Nephsmart LLC in Little Rock, AR. The grant, awarded on August 1, 2024, with a completion date of July 31, 2025, will support the development and testing of a point-of-care device to predict the risk of severe acute kidney injury (AKI). The device will detect cleavage of a specific...
This federal Project Grant award, totaling $641,873.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The goal of this 4-year award, which runs from September 1, 2024 to June 30, 2028, is to conduct a trans-omics analysis of African American deceased donor kidneys to optimize the allocation of kidneys from donors with high-risk genetic variants in the APOL1...
This $645,599 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under its Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to explore the use of dicarboxylic acid (DCA) supplementation as a therapy to prevent and treat acute kidney injury (AKI) and block the progression to chronic kidney disease (CKD). The research aims to demonstrate how DCA metabolically...
This federal Project Grant award of $117,000 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) will support research at the University of Michigan to investigate the role of the transcription factor PAX8 in controlling sensitivity to ischemic kidney injury in the proximal tubule. The key goals of this 2-year project are to: 1) determine how PAX8 expression regulates the...
This federal Project Grant award of $571,107 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant will support research to examine the role of complement activation in sepsis-associated acute kidney injury (SA-AKI) in critically ill children and adults. The key objectives are to: 1) determine the association between urine complement factor Bb levels...