Project Grant R01DE034406
- This Project Grant award of $965,145, provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research (CFDA 93.121) program, aims to examine disparities in oropharyngeal cancer (OPC) outcomes among Medicaid-enrolled adults. The key objectives are to: Characterize differences in early-stage diagnosis and 5-year survival rates for OPCs based on race, ethnicity, sex, and rurality using the SEER-Medicaid dataset. Assess the impact of...
- This federal Project Grant award of $483,360.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), will fund research to target vulnerabilities in the EGFR/HER3/HER2 oncogenic signaling circuitry for developing new precision therapies for oral cancer. The project aims to explore synthetic lethal and gene interaction networks to expose druggable systems vulnerabilities and uncover mechanisms of...
- This $681,331 Cooperative Agreement award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, supports a clinical trial to test the effectiveness of an intensive preventive dental program administered in oncology practices to reduce dental disease and improve oral health-related quality of life in head and neck cancer patients receiving radiation therapy. The key products and services to be delivered under...
- This $622,744 Project Grant was awarded by the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) federal grant program. The grant will fund research to investigate the role of the TRPM2 protein in the development of radiation-induced oral mucositis (RIOM), a common and painful side effect of radiation therapy for head and neck cancer. The research aims to understand how TRPM2 activation contributes to RIOM through the...
- This $550,296 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), aims to develop a multimodal imaging diagnostic platform to improve risk assessment of precancerous oral lesions. The key products and services to be delivered under this grant include: Development of machine learning and deep learning models using Fourier transform infrared (FTIR) imaging techniques for risk...
- This Project Grant award, identified as R03OD038393, was provided by the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121). The $1 award will fund the development of a machine learning tool using Visible Neural Networks (VNN) to enhance the explanatory power of knowledge graphs derived from data in the Common Fund Data Ecosystem (CFDE) for translating genome-wide association study (GWAS) results into actionable...
- The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $1,465,026 Project Grant on April 8, 2025 under the Oral Diseases and Disorders Research program (CFDA 93.121) to The University of Texas M.D. Anderson Cancer Center. The grant, titled "Harvard MD Anderson Collaborative to Reduce Lymphatic Morbidity in Head and Neck Cancer with Artificial Intelligence (HARMONIC-AI)," aims to leverage computational imaging and AI to enhance the detection and management of...
- This Project Grant award of $452,967.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports the development of a novel, robot-integrated system for intraoperative creation and annotation of digital 3D models of resection specimens and the residual tumor bed. The goal is to improve the management of positive surgical margins in the resection of oropharyngeal squamous cell carcinoma, which can...
- The University of Texas Health Science Center at Houston received a $722,040 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research Federal Grant Program (CFDA 93.121). The grant, titled "FULLMOUTH: Enhancing Dental Clinical Data and Reducing Disparities Through Innovative ML Approaches", aims to utilize natural language processing and machine learning techniques to extract meaningful insights from...
- This $598,332 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research (CFDA 93.121) program, will support research to investigate the role of the truncated TrkB isoform (TrkBT1) in oral cancer pain. The primary awardee, the University of Texas Health Science Center at San Antonio (UTHSCSA), will conduct studies to examine how TrkBT1 expressed in trigeminal sensory neurons and oral squamous cell carcinoma (OSCC)...
This Project Grant award of $736,507 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) supports the "ONTOLOGY-BASED APPLICATIONS OF MULTI-DISCIPLINARY KNOWLEDGE ON ORODENTAL CONDITIONS AND OUTCOMES (OPULENCE)" research project. The project aims to bridge unmet needs in reporting and conceptualizing orodental sequelae, such as osteoradionecrosis and post-radiation caries, that commonly occur in head and neck cancer survivors following radiation therapy. Key products and services to be delivered include: The award has an initial start date of August 1, 2025 and an ultimate completion date of May 31, 2030, spanning a multi-institutional and multidisciplinary research effort led by The University of Texas MD Anderson Cancer Center.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $736.5k | 7/30/25 |