Project Grant R01DE016416

Florida Atlantic University received a three-year, $753,464 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program to develop a multi-enzyme-mimicking bioceramic material for enhanced cell functions. The university will study whether doping manganese dioxide nanoparticles into calcium phosphate ceramic scaffolds retains the unique enzyme-mimicking functions of manganese dioxide while enhancing properties of the biomaterial. Researchers will prepare...

This National Science Foundation (NSF) Division of Materials Research Project Grant, CFDA# 47.049 Mathematical and Physical Sciences, provides $400,000 in funding to The Trustees of the University of Pennsylvania to conduct collaborative research on developing novel hybrid metal-piezoelectric biomaterials for anti-infectious implantable medical devices. The key objective is to create advanced multifunctional biomaterial platforms that can effectively prevent biofilm formation and bacterial...

The National Science Foundation's Division of Materials Research awarded a 3-year, $500,000 project grant to the University of Alabama at Birmingham (UAB) to develop advanced polymeric materials with precisely controlled physical properties and hierarchical nanostructured architectures. The research aims to understand how the internal organization of polymer networks affects the mechanical, swelling, and surface properties of thin hydrogel coatings. Key objectives include: (A) studying the...

This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) will support research to develop a platform for encapsulating biologic agents like bone morphogenic protein 2 (BMP-2) within hydrophobic polymer matrices. The $388,575 award to Rutgers, The State University, with a performance period from August 2024 to July 2026, aims to...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Magsorbeo Biomedical Corp. aims to develop a bioabsorbable magnesium alloy for maxillofacial fixation implants. The innovation seeks to improve healthcare outcomes by eliminating the need for secondary surgeries to remove permanent metal implants, which occur in 5-20% of maxillofacial fixation cases and cost the U.S. healthcare system $1.72 billion annually. This Phase...

This CAREER project grant, awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049), aims to develop a novel magnetoelectric biomaterial that can replicate the complex mechanical and electrical properties of human bones. The $113,932 award to Boise State University will support the following key objectives: Printing 3D porous scaffolds using the magnetoelectric biomaterial, replicating the structure and strength of natural bone tissue....

North Carolina A&T State University will conduct research on biodegradable composite nanofiber meshes containing degradable metal particulates under a $550,000 Project Grant from the National Science Foundation (NSF) Office of Integrative Activities. The three-year grant was awarded on June 15, 2021 with a completion date of May 31, 2024. The research is funded through the NSF's Mathematical and Physical Sciences program (CFDA 47.049), which supports progress in these scientific fields to...

The federal Project Grant award R03TR004613, funded by the National Center for Advancing Translational Sciences (NCATS - CFDA 93.350), aims to develop novel multiscale bone scaffolds using inorganic polymer materials for bone tissue regenerative engineering. The $141,478 award to North Carolina State University will fund research to optimize the synthesis of biocompatible inorganic polymer-based scaffolds, explore the mechanisms of cell attachment and migration, and investigate the ability of...

The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $243,750 Project Grant under the Oral Diseases and Disorders Research program (CFDA 93.121) to The Trustees of the University of Pennsylvania (UPenn) to explore the use of ferumoxytol nanoparticles to activate orofacial mesenchymal stem/progenitor cells (OMSCs) and promote their regenerative capabilities for craniofacial tissue repair. The grant aims to determine how ferumoxytol, an FDA-approved iron oxide nanoparticle,...

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $1,582,671.00 to the University of Connecticut to develop a novel bionic bone composite scaffold (BBCS) for reconstructing large and major bone defects. The BBCS is designed to be a completely biodegradable, battery-free, and remotely-activated scaffold that can...