This federal Project Grant award of $713,170.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA program 93.173 "Research Related to Deafness and Communication Disorders" aims to develop a multimodality micro-optical coherence tomography (MM-MOCT) imaging technology for visualizing the functional microanatomy of the human cochlea. The project, titled "Multimodality Micro-Optical Coherence Tomography for Imaging the Functional...
This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 "Research Related to Deafness and Communication Disorders" provides $637,500.00 to the Massachusetts Eye and Ear Infirmary to conduct research on understanding human cochlear micromechanics. The goal is to study the forward transduction that drives inner and outer hair cell stereocilia, as well as the reverse transduction that amplifies organ of Corti motion...
This federal Project Grant award of $111,513 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) supports a coordinated study of human cochlear anatomy and pathology. The project will use optical coherence tomography (OCT) to image and measure the motion of fresh, unfixed human cochlear structures in their natural state, without invasively accessing the cochlea. This research aims to expand the...
This federal Project Grant award of $610,725.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant will fund research at the University of Pittsburgh to investigate physiological mechanisms that contribute to suprathreshold deficits in speech understanding for individuals with sensorineural hearing loss. The key research activities include:...
This Project Grant award, valued at $377,700.00, was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The goal of the research is to develop and validate a reliable clinical decision support tool for early risk stratification of cochlear implant (CI) speech perception performance. The project aims to integrate novel biomarkers, patient comorbidities, and social...
The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $521,432 Project Grant under the CFDA 93.173 Research Related to Deafness and Communication Disorders program to the University of Rochester. The grant supports the development of a new computational model of the human auditory subcortex that integrates binaural processing and efferent gain control to investigate masking in complex sounds for both normal-hearing and hearing-impaired listeners. The research...
This federal Project Grant award of $781,703, awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 "Research Related to Deafness and Communication Disorders", supports research to better understand sensory development in human cochlear organoids. The goals are to define the developmental trajectories of key sensory cell types, test methods to increase the number of hair cells, and accelerate the maturation of hair cells and sensory...
This federal Project Grant award of $477,660 from the National Institute on Deafness and Other Communication Disorders (CFDA 93.173 - Research Related to Deafness and Communication Disorders) supports research to investigate age-related brain differences that affect speech recognition in older adults. The primary objectives are to characterize how quickly older adults accumulate sensory evidence and how much evidence they require to make speech recognition decisions, and to link these perceptual...
This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $251,856 to New York University from September 1, 2024 to August 31, 2026. The funding supports research investigating the neuroplastic processes underlying early adaptation to cochlear implants, which restore hearing and speech perception in individuals with severe or profound...
This federal Project Grant award of $673,048 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The objective is to investigate the role of mitochondrial calcium regulation in cochlear hair cells and its contribution to acquired hearing loss, with a focus on assessing the impact of acoustic overstimulation and developing strategies to mitigate noise-induced...
This federal Project Grant award of $711,342.00, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA program 93.173 "Research Related to Deafness and Communication Disorders", supports the development of high-fidelity clinical imaging techniques for the inner ear using photon counting detector computed tomography (PCD-CT) and advanced artificial intelligence (AI) algorithms.
The goal is to create high-resolution, artifact-free in vivo imaging capabilities to reliably diagnose and manage inner ear disorders such as superior semicircular canal dehiscence syndrome and cholesteatomatous labyrinthine fistula. The project will leverage the research team's expertise in PCD-CT and AI to reduce image noise, improve spatial resolution, and lower radiation dose for CT imaging of the inner ear. The research will be conducted at the Mayo Clinic in Rochester, Minnesota, with a project period from July 1, 2025 to June 30, 2030.