Project Grant R01DA063296

Award Date 7/15/25
Completion Date 3/31/30
Dollars Obligated $587K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Ohio, USA
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This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports a research study focused on understanding the impact of the opioid fentanyl on individuals with HIV. The total funding amount is $587,188, with the award period running from July 15, 2025 to March 31, 2030.

The key products and services to be delivered under this grant include:

  • A multi-omics approach and complementary in vivo and ex vivo studies to directly evaluate the impact of fentanyl on markers of the single cell transcriptome and microRNA profile in individuals with HIV and active drug use.
  • Translational research on opioid-cell and opioid-virus interactions to optimize treatment and limit viral reactivation, which is essential given the significant increase in drug overdose deaths involving opioids, particularly fentanyl, in recent years.
  • The research will be conducted by the University of Cincinnati, a premier public research institution, through its Sponsored Research Services Division.

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