Project Grant R01DA061796
- Federal Project Grant Award Summary Boston University Medical Campus received a $109,076 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded January 9, 2026, with completion targeted for July 31, 2029. The grant supports basic neuroscience research investigating the role of G alpha Z (GAZ) protein in mediating behavioral responses to opioids. The research aims to elucidate how GAZ signaling in specific brain...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Maryland, Baltimore a $685,937 Project Grant effective March 15, 2026, through December 31, 2030, under the Drug Use and Addiction Research Programs (CFDA 93.279). This research project investigates the impact of opioid use disorder (OUD) on mitochondrial dysfunction among antiretroviral therapy-receiving aging people with HIV (PWH). The study addresses a critical gap in understanding how...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Maryland, Baltimore a Project Grant of $219,291 under the Drug Use and Addiction Research Programs (CFDA 93.279) on September 30, 2025, for implementation of the Integrated Services for People Who Inject Drugs (PWID) Using Person-Centered Interactions, Reach, and Engagement (INSPIRE) study. This three-year initiative (completion date July 31, 2028) addresses critical gaps in HIV prevention and...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Johns Hopkins University a Project Grant totaling $466,363 under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct fundamental research on mu-opioid receptor (MOR) pharmacology and allosteric modulation mechanisms. The grant, awarded June 1, 2026, with completion targeted for April 30, 2031, supports research aimed at elucidating how endogenous neuromodulators such as endocannabinoids and...
- Federal Grant Award Summary The University of Maryland, Baltimore received a $428,432 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) effective September 1, 2025, through August 31, 2026. This award funds research combining experimental, computational, and artificial intelligence (AI) approaches to interrogate the pharmacology and mechanisms of action of fentanyl and nitazene...
- Federal Grant Award Summary The University of Pennsylvania received a $247,702 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded July 31, 2025, with completion targeted for January 31, 2028. The grant funds basic neuroscience research investigating the role of mu-opioid receptors in the paraventricular nucleus of the thalamus (PVT) in stress-related behavioral phenotypes and vulnerability to opioid use...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of California, San Diego a $1.39 million Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) effective March 1, 2026, with completion targeted for December 31, 2030. This grant supports research investigating mitochondrial oxidative phosphorylation dysfunction in the comorbid epidemics of HIV-Associated Neurocognitive Disorders (HAND) and Opioid Use Disorder (OUD) in the...
- Federal Grant Award Summary The University of Pennsylvania received a $1.56 million Project Grant from the National Institute on Drug Abuse under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the role of central amylin receptors in opioid-mediated behaviors. The award, effective July 1, 2025, through March 31, 2030, supports basic neuroscience research aimed at identifying novel druggable targets to address opioid use disorder (OUD) and reduce relapse rates...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded a Mentored Research Scientist Development Award (K01) totaling $399,600 to support a five-year career development and research initiative addressing opioid use disorder (OUD) treatment optimization. Led by Dr. Jason Brian Gibbons at the University of Colorado Anschutz Medical Campus, with performance conducted at Brigham & Women's Hospital, this award under the Drug Use and Addiction Research Programs (CFDA...
- Federal Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded the University of Maryland, Baltimore $1.92 million under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a five-year project (July 15, 2025 – March 31, 2030) investigating the behavioral and neurobiological mechanisms of reciprocal social interactions in substance use disorders (SUDs). The project will deliver foundational research aimed at bridging the gap between preclinical animal models and...
The National Institute on Drug Abuse (NIDA) awarded the University of Maryland, Baltimore a $659,796 R01 Research Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a rigorous, double-blind, placebo-controlled human laboratory trial examining the co-use of opioids and gabapentin. The five-year project, initiated June 1, 2026 and concluding February 28, 2031, will deliver mechanistic research and clinical evidence on the risks and therapeutic benefits of combined opioid-gabapentin polypharmacy among individuals with chronic lower back pain and a history of opioid use. The study will evaluate the effects of gabapentin and hydromorphone—administered individually and in combination—on non-medical use risk, acute and chronic pain management, stress responses, and physiological outcomes to complement existing epidemiological and case study literature on this medication combination. This research directly addresses the ongoing opioid epidemic by identifying safer pain management approaches and mitigating prescription opioid risks. The project responds to emerging evidence suggesting gabapentin's non-medical use risk may be greater than previously suspected, particularly among individuals with opioid use histories. The deliverables include human laboratory trial data, mechanistic findings on drug interactions, and evidence-based recommendations for clinical decision-making regarding opioid-gabapentin co-prescription in chronic pain treatment.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 6/3/26 | ||
| Not listed | $659.8k | 5/28/26 |