Project Grant R01DA060253
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Medical University of South Carolina a Project Grant of $139,851 under the Drug Use and Addiction Research Programs (CFDA 93.279) on October 10, 2025, with a completion date of April 30, 2028. This award supports preclinical research investigating the therapeutic potential of psilocybin in reducing stress-cued relapse in opioid use disorder (OUD). The research addresses a critical gap in understanding how...
- Federal Grant Award Summary The University of Oregon received a $406,051 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective June 15, 2025 through May 31, 2027. This research award supports a genetic analysis study investigating psychoplasticity in Caenorhabditis elegans to advance understanding of how psychedelic compounds may treat intractable psychiatric diseases, including depression,...
- Federal Project Grant Award Summary Princeton University received a $246,000 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded June 15, 2025, with completion targeted for May 31, 2027. The grant supports fundamental neuroscience research investigating the systems-level brain mechanisms underlying psilocybin's therapeutic potential for treating anxiety, depression, addiction, pain, and illness-associated...
- Federal Grant Award Summary New York University School of Medicine received a $871,225 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded March 1, 2026, with completion targeted for November 30, 2030. The award funds a clinical research study investigating psilocybin as a novel therapeutic intervention for residual anhedonia (loss of pleasure or interest) in patients currently taking selective serotonin...
- Federal Project Grant Award Summary Oregon Health & Science University received a $429,000 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop innovative tools for studying tetrahydrocannabinol (THC) signaling in brain reward circuits. The award, effective July 15, 2025 through June 30, 2027, supports research into the molecular mechanisms by which THC affects addictive behaviors through the development of...
- Federal Project Grant Award Summary Cornell University's Office of Sponsored Programs received a $149,804 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a three-year research initiative from April 1, 2025, through March 31, 2028. The research focuses on elucidating the neural mechanisms of psilocybin action in the frontal cortex, with specific emphasis on GABAergic (gamma-aminobutyric acid-releasing)...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $791,990 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective June 15, 2025, with an ultimate completion date of April 30, 2030. The award supports a three-week prospective, mechanistic randomized controlled study examining the bidirectional relationships between cannabis use, sleep, and the hypothalamic-pituitary-adrenal...
- Federal Grant Award Summary Psilera, Inc. received a $960,789 Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) under the Alcohol Research Programs (CFDA 93.273), with an award date of September 15, 2025 and completion date of February 28, 2026. The grant supports the development and characterization of a novel non-hallucinogenic psilocybin derivative for the treatment of alcohol use disorder. The research involves structure-activity relationship analyses of...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $453,062 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), effective September 1, 2025, through May 31, 2030. The research project, titled "Control of Opioid Receptor Signaling and Pharmacological Tolerance Through Endosomal Recycling and Retromer," investigates cellular mechanisms underlying opioid tolerance—the...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $1.54 million Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a comprehensive research study examining the impact of telehealth expansion on opioid use disorder (OUD) treatment delivery within community health centers. The award, effective July 1, 2025, through March 31, 2030, will utilize nearly a decade of electronic...
The National Institute on Drug Abuse (NIDA) awarded Oregon Health & Science University a Project Grant valued at $736,713 under the Drug Use and Addiction Research Programs (CFDA 93.279) effective February 15, 2026, with completion targeted for November 30, 2030. The Psilocybin Research and Implementation Study for Mental Health and Substance Use (PRISM) will conduct a rigorous longitudinal research study assessing the safety and effectiveness of state-regulated psilocybin services in real-world community settings. OHSU will enroll individuals with substance use disorders receiving Oregon's psilocybin services and compare them to a control group over a 12-month observation period using surveys and qualitative interviews. The study delivers three primary research products: (1) an assessment of safety events and potential adverse outcomes associated with regulated psilocybin services in substance-using populations; (2) analysis of the impact on substance use outcomes, including identification of specific substances and subpopulations that may respond favorably to treatment; and (3) qualitative stakeholder feedback on long-term safety implications and substance use changes. By generating evidence-based data on the safety profile and therapeutic impact of these emerging services before broader policy expansion, PRISM will inform voter and policymaker deliberations regarding psychedelic-assisted treatment programs across multiple states currently considering similar legislation.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $736.7k | 2/3/26 |