Project Grant R01MH142698
- Federal Project Grant Award Summary Princeton University received a $246,000 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) awarded June 15, 2025, with completion targeted for May 31, 2027. The grant supports fundamental neuroscience research investigating the systems-level brain mechanisms underlying psilocybin's therapeutic potential for treating anxiety, depression, addiction, pain, and illness-associated...
- Federal Project Grant Award Summary Cornell University's Office of Sponsored Programs received a $149,804 Project Grant from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a three-year research initiative from April 1, 2025, through March 31, 2028. The research focuses on elucidating the neural mechanisms of psilocybin action in the frontal cortex, with specific emphasis on GABAergic (gamma-aminobutyric acid-releasing)...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded The Medical University of South Carolina a Project Grant of $139,851 under the Drug Use and Addiction Research Programs (CFDA 93.279) on October 10, 2025, with a completion date of April 30, 2028. This award supports preclinical research investigating the therapeutic potential of psilocybin in reducing stress-cued relapse in opioid use disorder (OUD). The research addresses a critical gap in understanding how...
- Federal Grant Award Summary The National Institute of Mental Health (NIMH) awarded The Feinstein Institutes for Medical Research a Project Grant of $519,558 under the Mental Health Research Grants program (CFDA 93.242), effective June 15, 2025 through April 30, 2030. The research project focuses on identifying and validating cerebellar-cortical circuitry biomarkers as predictive indicators of antipsychotic treatment response in first-episode psychosis patients. The primary deliverables...
- Federal Project Grant Award Summary New York University School of Medicine received a $815,251 project grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), effective June 1, 2025, through March 31, 2030. The award funds a comprehensive evaluation of Medicaid Delivery System Reform Incentive Payment (DSRIP) programs and their impacts on healthcare utilization, care coordination, and health outcomes among Medicaid enrollees with...
- Federal Project Grant Award Summary The National Institute of Mental Health (NIMH) awarded $394,200 to the Research Foundation For Mental Hygiene, Inc. (RFMH) on August 1, 2025, under the Mental Health Research Grants program (CFDA 93.242) to conduct a five-year clinical research study examining the role of the anterior hippocampus in major depressive disorder (MDD) pathogenesis. The project utilizes functional magnetic resonance imaging (fMRI) and an emotional pattern separation task to...
- Federal Grant Award Summary New York University received a $633,438 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) on June 16, 2025, with a completion date of March 31, 2030. The award supports research on data-driven control of primate prefrontal neural activity using patterned microstimulation. The project addresses a critical gap in neuroscience and neuroengineering by developing a data-driven framework for...
- Federal Grant Award Summary New York University School of Medicine is conducting research on "Tailoring Nanocrystals as a Versatile Platform for Noninvasive Neuroengineering" under a $1.34M Project Grant from the National Institute of Mental Health (NIMH) Mental Health Research Grants program (CFDA 93.242). Awarded September 19, 2025, with completion targeted for August 31, 2028, this research initiative develops molecularly engineered nanocrystals capable of converting...
- Grant Award Summary The University of Pennsylvania received a $137,894 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, with an award date of May 9, 2025 and completion date of December 31, 2025. This research project investigates the cortical mechanisms by which psilocybin ameliorates chronic pain disorders, addressing a critical public health...
- Federal Project Grant Award Summary The National Institute on Drug Abuse (NIDA) awarded Oregon Health & Science University a Project Grant valued at $736,713 under the Drug Use and Addiction Research Programs (CFDA 93.279) effective February 15, 2026, with completion targeted for November 30, 2030. The Psilocybin Research and Implementation Study for Mental Health and Substance Use (PRISM) will conduct a rigorous longitudinal research study assessing the safety and effectiveness of...
New York University School of Medicine received a $871,225 Project Grant from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), awarded March 1, 2026, with completion targeted for November 30, 2030. The award funds a clinical research study investigating psilocybin as a novel therapeutic intervention for residual anhedonia (loss of pleasure or interest) in patients currently taking selective serotonin reuptake inhibitors (SSRIs). The research will conduct a randomized controlled trial administering either a single 25 mg dose of psilocybin or a 1 mg control dose to eligible participants experiencing SSRI-induced anhedonia. The project delivers research services centered on advancing understanding of psilocybin's neural mechanisms of action through precision functional magnetic resonance imaging (fMRI) mapping. Specifically, the investigation will characterize how psilocybin modulates fronto-limbic brain circuits—particularly the pregenual anterior cingulate cortex and nucleus accumbens connection that comprises the brain's core reward system—to alleviate anhedonia symptoms. This research directly addresses a significant clinical gap, as current first-line antidepressants often suppress emotional and reward processing despite improving mood, whereas emerging evidence suggests psilocybin may offer superior efficacy in restoring emotional range and motivation in treatment-resistant populations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $871.2k | 2/19/26 |