Project Grant R01DA058994

Award Date 9/15/24
Completion Date 7/31/29
Dollars Obligated $772K
Federal Grant Program
93.279
Assistance Type
Project Grant
Place of Performance
Kingston, RI 02881, USA

The University of Rhode Island (URI) Research Office received a $771,618 project grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) to evaluate the spillover effects of HIV interventions among marginalized populations, particularly young Black men who have sex with men (BMSM) who use illicit substances.

The key products and services to be delivered under this 5-year grant include:

  • Secondary data analyses of existing network studies (UCONNECT, PrEP Chicago, Neighborhood and Networks Cohort Study) to assess spillover of HIV interventions in this population
  • Development of sample size and power formulas to evaluate spillover in sociometric network-based studies
  • Causal methods to address network dependence and missing data threats in assessing spillover
  • A pre-deployment evaluation of spillover for HIV interventions, including PrEP peer change and PrEP delivery, using an agent-based network model of young BMSM in Chicago

This project aims to provide new insights into the spillover effects of HIV interventions and facilitate the conduct of adequately powered future studies to determine the most effective HIV interventions for young BMSM who use illicit substances. The transdisciplinary research team will leverage URI's expertise and resources to advance modeling and statistical methodology to improve HIV prevention and treatment in this marginalized population.

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