Project Grant R01CA315474
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Children's Hospital of Philadelphia $749,133 under the Cancer Cause and Prevention Research program (CFDA 93.393) for a Project Grant beginning June 1, 2026, through May 31, 2031. The award funds development and evaluation of DECIDES 2.0 (AYA Deciding About Cancer Clinical Intervention: Decision Aid for Education and Support), an enhanced interactive mobile-friendly web-based decision support tool designed to improve...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Washington University a $425,088 Project Grant effective May 1, 2026, through April 30, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). This research initiative will deliver a comprehensive evaluation of lung cancer care quality and treatment outcomes for Medicare-eligible older adults, comparing delivery patterns and clinical outcomes between Traditional Medicare (fee-for-service) and...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Regents of the University of Colorado a $656,046 Project Grant on August 1, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a randomized controlled trial of EASE (Exposure-based Anxiety and Symptom Elimination), a novel behavioral intervention designed to reduce fear of cancer progression (FOP) and cancer-related trauma symptoms in adults with advanced cancer. The five-year...
- Federal Grant Award Summary The National Cancer Institute awarded a $731,503 Project Grant to Sloan-Kettering Institute for Cancer Research, effective June 1, 2026 through May 31, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). The award funds a randomized controlled trial (RCT) evaluating Brief Behavioral Activation for Older Adult Cancer Survivors (BBA-OACS), a telehealth-based psychotherapy intervention designed to address clinically significant depression among...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a Project Grant totaling $203,542.00 to The Washington University, Office of Sponsored Research Services, effective July 1, 2025, through June 30, 2027, under the Cancer Research Manpower program (CFDA 93.398). This award supports a two-year research initiative investigating the impact of clonal hematopoiesis (CH)—specifically TET2-mutant hematopoietic cells—on solid tumor development and therapeutic response. The research...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Washington University a Project Grant totaling $645,185 under the Cancer Treatment Research program (CFDA 93.395) on May 15, 2026, with completion targeted for April 30, 2031. This research initiative, titled "Expand and Pull: Long-Acting IL-7 and Oncolytic Virus to Treat Glioblastoma," will develop and evaluate a novel combination immunotherapy approach for glioblastoma, an aggressive brain tumor with a median...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded Ann & Robert H Lurie Children's Hospital of Chicago a $651,859 Project Grant on September 19, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop and evaluate #AYAOSM (The AYA Oncology Self-Care Movement), an influencer-driven social media intervention designed to improve oral chemotherapy adherence in adolescents and young adults (AYAs) with acute lymphoblastic leukemia. Prior...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Johns Hopkins University a $105,076 Project Grant under the Cancer Research Manpower program (CFDA 93.398) effective February 15, 2026, with a completion date of August 14, 2027. This award funds a multi-method research investigation examining electronic communication (e-communication) between pediatric cancer caregivers and healthcare teams. The study will analyze the frequency, modes, and quality of...
- Federal Project Grant Award Summary The National Cancer Institute awarded The MGH Institute of Health Professions, Inc. a $696,498 Project Grant (CFDA 93.393 - Cancer Cause and Prevention Research) effective May 1, 2026, through April 30, 2031, to develop and optimize a multicomponent intervention designed to improve functional recovery and quality of life among breast cancer survivors. The research employs the Multiphase Optimization Strategy (MOST) framework to systematically evaluate three...
- Federal Project Grant Award Summary The National Cancer Institute awarded The Washington University in St. Louis a $399,829 Project Grant effective May 13, 2026, through April 30, 2028, under the Cancer Treatment Research program (CFDA 93.395). The award supports research and development of a novel dendritic cell (DC)-based immunotherapy designated AB7H3-TLR4 CAR-DCs. This therapeutic approach involves engineering dendritic cells to express a B7H3-specific chimeric antigen receptor (CAR) fused...
The National Cancer Institute (NCI) awarded Washington University in St. Louis a $656,181 Project Grant on June 19, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop and evaluate the Communication and Hospice Online with Optimal Support and Engagement (CHOOSE) intervention. This five-year initiative (completion date: May 31, 2031) represents the first major, multisite, rigorously designed online support group (OSG) intervention explicitly tailored for family caregivers (FCGs) of hospice cancer patients. The research leverages social identity theory to identify and test facilitator communication strategies that strengthen mechanisms of action—including shared identity, social support, and social networks—within OSGs to enhance health outcomes for hospice FCGs. The deliverables include rigorous empirical evidence through three primary study aims: determining the comparative effectiveness of the CHOOSE intervention on FCG health outcomes (depression, anxiety, quality of life, and loneliness reduction), examining the direct and mediational relationships between intervention participation and mechanisms of action, and exploring the relationship between facilitator communication strategies and FCG experience to enable future intervention calibration. This research addresses a critical gap in the existing literature by providing a theoretically informed, evidence-based solution grounded in statistical rigor and generalizability—advancing supportive care strategies for an underserved population of hospice family caregivers.Federal Grant Award Summary: CHOOSE Initiative
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $656.2k | 6/19/26 |