Project Grant R01CA308143
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $370,173 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393), awarded September 9, 2025, with a completion date of August 31, 2030. This project delivers research and development of advanced genetic interaction measurement and characterization methodologies for cancer cells, with a primary focus on synthetic lethality as a...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $825,966 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393), awarded September 4, 2025, with a completion date of August 31, 2030. The RISE (Reducing Cancer and HIV Stigma Through Empowerment) project delivers a multilevel, culturally adapted storytelling intervention designed to address dual stigma experienced by Zambian women living with...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded MD Anderson Cancer Center a $421,685 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) for the period June 1, 2026, through May 31, 2028. This research initiative addresses methodological gaps in risk assessment for rare cancer patients by developing advanced statistical frameworks that leverage information from multiple data sources. The project will deliver two novel transfer-learning-based...
- Federal Grant Award Summary The National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), awarded a $401,115 Project Grant to the University of Texas Health Science Center at Houston, effective May 1, 2026, through April 30, 2028. The project, titled "Identifying Mechanisms of Implementation Strategies for Cancer Control: An Implementation Mapping Approach," aims to address the persistent research-to-practice gap in cancer prevention and...
- Federal Grant Award Summary The National Cancer Institute awarded The University of Texas MD Anderson Cancer Center a $420,400 Project Grant under the Cancer Treatment Research program (CFDA 93.395) effective August 1, 2025, through July 31, 2027. This award supports exploratory studies investigating cellular resistance mechanisms to second-generation MTA-cooperative PRMT5 inhibitors (MTA:PRMT5I) in MTAP-loss tumors. The research addresses a critical clinical challenge whereby 40-60% of patients...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded MD Anderson Cancer Center a $688,073 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective June 1, 2026, through May 31, 2031. The award funds computational research to reconstruct the evolutionary history of cancer metastases, led by Principal Investigator Dr. Peter Van Loo. The project develops novel molecular archeology of cancer approaches—computational methods that leverage DNA sequencing...
- Summary of Federal Project Grant Award Award Details: The National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), awarded a Project Grant of $696,924 to The University of Texas MD Anderson Cancer Center effective July 1, 2026, through June 30, 2031. Products and Services: This grant funds research assessing immune responses to neoantigen vaccination in Lynch Syndrome (LS), the most common cause of hereditary colorectal and endometrial cancer...
- Project Grant Summary Georgetown University received a $663,383 Project Grant award from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) on August 1, 2025, to support proactive outreach and streamlined genetic testing initiatives for prostate cancer survivors. The project, extending through July 31, 2030, addresses the critical gap between expanded germline genetic testing guidelines and low testing rates among the nation's over three million...
- Federal Project Grant Award Summary The University of Texas MD Anderson Cancer Center received a $421,685 project grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), awarded August 1, 2025, with a completion date of July 31, 2027. This award supports research investigating the LIFR-LCN2 pathway as a novel mechanism of immune suppression in hepatocellular carcinoma (HCC). The research aims to elucidate how loss of LIFR upregulates LCN2, leading to...
- Federal Grant Award Summary The National Cancer Institute awarded a $680,600 Project Grant to The University of Texas MD Anderson Cancer Center on September 19, 2025, under the Cancer Cause and Prevention Research program (CFDA 93.393) to develop and evaluate a family-centered lifestyle intervention for Black prostate cancer survivors and their caregivers. The grant supports a randomized controlled trial examining the efficacy of a dyadic-focused intervention designed to improve physical...
The University of Texas MD Anderson Cancer Center received a $706,777 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) for the five-year period from July 1, 2026 through June 30, 2031. The IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) initiative addresses the underdiagnosis of hereditary cancer syndromes, including hereditary breast and ovarian cancer and Lynch syndrome, by developing and evaluating an intervention designed to increase cascade genetic testing (CGT) uptake among underserved populations with limited access to hereditary cancer services. The project will recruit 700 probands (affected individuals) and 1,400 at-risk relatives nationwide to participate in a randomized hybrid effectiveness-implementation trial comparing four intervention arms: usual care, free genetic counseling and testing alone, IGNITE-TX intervention, and IGNITE-TX combined with free services. The core deliverables include evaluation of CGT uptake rates at six months, assessment of psychosocial and behavioral outcomes including genetic knowledge and family communication improvements, and formative and process evaluations to optimize implementation and ensure scalability across low-resource and safety-net healthcare settings. The intervention employs family genetic navigators and web-based educational tools as mechanisms to enhance hereditary cancer prevention. Study outcomes will inform dissemination strategies aligned with the RE-AIM QUEST implementation framework, producing evidence-based practices that can be replicated in resource-constrained clinical environments to identify and support individuals at genetic risk for hereditary cancers.IGNITE-TX Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $706.8k | 6/25/26 |