Project Grant R01CA307125
- Federal Grant Award Summary Wayne State University received a $155,000 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) effective May 1, 2026, through April 30, 2028. This research initiative addresses a critical gap in cervical cancer (CC) prevention by investigating multi-level predictors of diagnostic follow-up (DFU) attendance after abnormal cervical cancer screening. While the United States has made progress toward Human...
- Federal Project Grant Award Summary Wayne State University received a $183,309 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398) effective August 1, 2025, through July 31, 2030. The grant supports a research investigation examining socio-genomic associations related to survival outcomes among women diagnosed with endometrial cancer in the Detroit metropolitan area. The project aims to understand why certain high-risk populations...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the Regents of the University of Michigan $175,448 under the Cancer Research Manpower program (CFDA 93.398) on January 16, 2026, with completion targeted for July 31, 2027. This project grant supports research training and investigator development in cancer biology, specifically focused on characterizing cancer-associated fibroblasts (CAFs) and their role in pancreatic ductal adenocarcinoma (PDAC). The research aims to...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded $128,199 to the Regents of the University of Michigan through the Cancer Research Manpower program (CFDA 93.398) effective December 1, 2025, with a completion date of May 31, 2027. This project grant supports biomedical research training and career development in cancer research aligned with the National Cancer Program's strategic priorities. The funded research, titled "Deciphering the Functional Role of PPP2R1A...
- Federal Grant Award Summary Michigan State University (through its Henry Ford Health+Michigan State University Health Sciences partnership) received a $153,278 Project Grant from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) effective July 3, 2025, with completion expected June 30, 2027. The award supports the development of a Dre-Rox recombination-based Genetically Engineered Mouse Model (GEMM) for NUT carcinoma, a rare but aggressive...
- Federal Project Grant Award Summary Wayne State University received a $401,833 Project Grant from the National Science Foundation's Division of Information and Intelligent Systems (CFDA 47.070, Computer and Information Science and Engineering program) awarded January 1, 2026, with completion targeted for June 30, 2027. The project delivers novel computational technologies and methodologies for integrative pathway analysis to improve cancer subtyping, patient stratification, and risk...
- Federal Grant Award Summary The National Cancer Institute awarded The Johns Hopkins University a $510,431 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective July 1, 2025 through June 30, 2030. This award supports fundamental research investigating the mechanisms of metastatic recurrence and therapeutic resistance in melanoma, with particular emphasis on understanding how aging influences tumor dormancy and the microenvironment. The research examines Wnt signaling...
- Federal Grant Award Summary The National Cancer Institute awarded a $646,881 Project Grant to the Regents of the University of Michigan (Office of Research and Sponsored Projects) under the Cancer Treatment Research program (CFDA 93.395) for the period April 1, 2026, through March 31, 2031. This research project focuses on developing and evaluating small molecule inhibitors targeting ASH1L (Absent, Small or Homeotic 1-Like), a histone methyltransferase protein implicated in acute leukemia...
- Federal Grant Award Summary The National Cancer Institute awarded the University of South Alabama a Project Grant totaling $369,868 under the Cancer Biology Research program (CFDA 93.396) to investigate intercellular mitochondrial transfer between nerve cells and triple-negative breast cancer (TNBC) cells at the nerve-cancer interface. Awarded on July 7, 2025, with a completion date of May 31, 2030, this research addresses the functional role of cancer neurogenesis in metastasis and tumor...
- Federal Grant Award Summary The National Cancer Institute awarded the University of Pittsburgh a $151,920 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective September 1, 2025, through August 31, 2027. This award supports fundamental research to develop and validate Nuclear Magnetic Resonance (NMR) strategies for investigating allosteric inhibitor binding effects on Src-family kinases implicated in acute myeloid leukemia (AML). The research aims to characterize...
The National Cancer Institute (NCI) awarded Wayne State University $371,024 under the Cancer Biology Research program (CFDA 93.396) on April 1, 2026, to support a five-year project through March 31, 2031. This project grant funds fundamental research investigating the essential roles of noncanonical signaling pathways of Janus Kinases 1 and 2 (JAK1 and JAK2) in mammary gland development and breast cancer. The research will employ genetically engineered mouse models to elucidate how JAK1 and JAK2 regulate postnatal mammary epithelial cell growth, differentiation, and survival through mechanisms independent of canonical Signal Transducers and Activators of Transcription (STAT) protein signaling. The project addresses a critical gap in current understanding by proposing that the biologically significant functions of these kinases are facilitated by noncanonical molecular signaling mechanisms rather than the well-established STAT-dependent pathways previously characterized in mammary epithelial tissues. The research will be conducted at Wayne State University's facility in Detroit, Michigan, under the Sponsored Project Administration Division. This Cancer Biology Research award supports investigator-initiated basic science research aimed at advancing understanding of cancer mechanisms with implications for improved prevention, detection, diagnosis, and treatment methodologies for neoplastic diseases. The findings are anticipated to contribute fundamental knowledge regarding the role of JAK-mediated signaling in both normal mammary gland physiology and breast cancer development.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $371.0k | 3/30/26 |