Project Grant R01CA300694
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $709,677 Project Grant from the National Cancer Institute under the Cancer Detection and Diagnosis Research program (CFDA 93.394) on June 5, 2026, to develop and validate advanced imaging technologies for improved prostate cancer mapping and treatment planning. The research focuses on integrating quantitative magnetic resonance imaging (QMRI) and prostate-specific membrane antigen positron emission tomography (PSMA-PET)...
- Federal Grant Award Summary Cedars-Sinai Medical Center received an $858,798 R21 Project Grant awarded on August 18, 2025, by the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) to support a two-year research initiative through July 31, 2027. The project, led by two principal investigators with complementary expertise, investigates the role of extracellular vesicles (EVs) enclosed circular RNA (circRNA) in modulating immune responses within the...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Trustees of Columbia University in the City of New York a Project Grant of $531,825 under the Cancer Biology Research program (CFDA 93.396) effective August 1, 2025, with completion targeted for July 31, 2030. This research initiative focuses on understanding the molecular mechanisms of castration sensitivity in prostate epithelium, with the ultimate goal of improving therapeutic responses to androgen-deprivation therapy...
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $501,000 Project Grant award from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) effective July 15, 2025, with a completion date of July 14, 2027. The research project, titled "Large Oncosomes as Drivers of Prostate Cancer Bone Metastasis," is being conducted at the institution's West Hollywood, California location. This award supports biomedical...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded Icahn School of Medicine at Mount Sinai a Project Grant totaling $714,317 under the Cancer Biology Research program (CFDA 93.396) to support fundamental research on prostate cancer progression and therapeutic resistance. The five-year award, effective August 1, 2025 through July 31, 2030, funds research investigating the molecular mechanisms linking epithelial-mesenchymal transition (EMT), mesenchymal-epithelial transition...
- Federal Grant Award Summary Cedars-Sinai Medical Center received a $2.1 million Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on "Enhancing Quality of Life Through Remote Patient Monitoring in Men Diagnosed with Advanced Prostate Cancer." The award, effective July 1, 2026, through June 30, 2030, will support clinical research and development activities focused on improving healthcare...
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $695,634 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) on May 7, 2026, with an anticipated completion date of April 30, 2031. This award funds research investigating the role of interleukin-27 receptor (IL27R) signaling and B cell-mediated immune responses in hepatocellular carcinoma (HCC) tumor microenvironments. The research program focuses on...
- Federal Project Grant Award Summary The National Cancer Institute awarded a $160,093 Project Grant to The Washington University (Office of Sponsored Research Services) effective May 1, 2026, through April 30, 2028, under the Cancer Cause and Prevention Research program (CFDA 93.393). This research initiative addresses risk-based prostate cancer (PCA) screening perceptions and informational needs among screening-eligible men, with particular emphasis on addressing health disparities affecting...
- Federal Grant Award Summary Cedars-Sinai Medical Center received a $191,700 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), effective September 1, 2025 through August 31, 2028. This award supports research investigating the etiology and tumor characteristics of early-onset pancreatic cancer. The project delivers two primary research products: (1) epidemiological analysis identifying modifiable risk factors associated with...
- Federal Project Grant Award Summary Cedars-Sinai Medical Center received a $679,353 Project Grant award from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), effective May 1, 2026 through April 30, 2031. This five-year research initiative investigates the protective role of PYDC5 protein in colorectal cancer development and progression. The research will elucidate how PYDC5 expression in intestinal macrophages influences the tumor immune...
Federal Grant Award Summary The National Cancer Institute awarded Cedars-Sinai Medical Center a $646,784 Project Grant on June 16, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct research examining the impact of exogenous hormone use on prostate cancer risk, detection, and clinical outcomes within the Veterans Affairs Health System. The research will investigate how estrogen intake in men affects prostate cancer screening rates, prostate-specific antigen (PSA) threshold abnormality definitions, cancer aggressiveness, and diagnostic patterns—with particular attention to disparities across racial and neighborhood demographics. Preliminary findings published by the investigative team suggest that men taking estrogen experience delayed prostate cancer diagnosis due to reduced PSA levels, necessitating revised diagnostic screening protocols distinct from those applied to men without exogenous hormone intake. This five-year project, extending through May 31, 2031, will leverage the Veterans Affairs Health System's nationwide patient database to develop evidence-based recommendations for optimizing prostate cancer screening and diagnosis in hormonally treated populations. The research supports the Cancer Cause and Prevention Research program's objectives to identify cancer risks, risk reduction strategies, and screening/early detection mechanisms while addressing health disparities in cancer diagnosis and outcomes across diverse veteran populations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $646.8k | 6/16/26 |