Project Grant R01CA300353
- Federal Project Grant Award Summary The National Cancer Institute awarded The Johns Hopkins University a $354,658 Project Grant under the Cancer Biology Research program (CFDA 93.396) effective August 1, 2025 through July 31, 2030. This award supports fundamental research investigating subclonal P27 (CDKN1B) loss as a driver of aggressive prostate cancer, with particular focus on understanding health disparities affecting Black or African American males who experience prostate cancer mortality...
- Federal Grant Award Summary The National Cancer Institute awarded The Johns Hopkins University a Project Grant of $130,301 under the Cancer Cause and Prevention Research program (CFDA 93.393), with an award date of September 5, 2025, and a project completion date of August 31, 2030. This award supports extensions to the Surveillance, Epidemiology, and End Results (SEER)-Medicare Database, a critical data linkage that connects Medicare claims with cancer registry enrollment data. The primary...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded The Johns Hopkins University a $512,728 Project Grant effective August 1, 2025, through May 31, 2030, under the Cancer Detection and Diagnosis Research Program (CFDA 93.394). The award supports development and clinical evaluation of PROBOT, a novel ultrasound probe and robotic system designed to improve image-guided interventions for prostate cancer diagnosis and treatment. The project encompasses a Phase 1...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Trustees of Columbia University in the City of New York a Project Grant of $531,825 under the Cancer Biology Research program (CFDA 93.396) effective August 1, 2025, with completion targeted for July 31, 2030. This research initiative focuses on understanding the molecular mechanisms of castration sensitivity in prostate epithelium, with the ultimate goal of improving therapeutic responses to androgen-deprivation therapy...
- Federal Grant Award Summary The National Cancer Institute awarded The Washington University a $160,093 Project Grant effective May 1, 2026, through April 30, 2028, under the Cancer Cause and Prevention Research program (CFDA 93.393). The grant supports research investigating perceptions and informational needs regarding risk-based prostate cancer screening among screening-eligible men. The research addresses disparities in prostate-specific antigen (PSA) screening practices, particularly among...
- Project Grant Summary Georgetown University received a $663,383 Project Grant award from the National Cancer Institute under the Cancer Cause and Prevention Research program (CFDA 93.393) on August 1, 2025, to support proactive outreach and streamlined genetic testing initiatives for prostate cancer survivors. The project, extending through July 31, 2030, addresses the critical gap between expanded germline genetic testing guidelines and low testing rates among the nation's over three million...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Pittsburgh a $649,620 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) effective May 1, 2026, through April 30, 2031. This research project examines the impacts of Medicare Advantage insurance coverage on cancer care access, quality, and outcomes for older adults with the four most prevalent cancers: breast, colorectal, lung, and prostate. The research addresses a...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded The Johns Hopkins University a Project Grant totaling $144,193 under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) on September 4, 2025, with a completion date of August 31, 2030. This award provides protected salary support for Dr. Preethi Korangath, a Laboratory Research Specialist in Dr. Robert Ivkov's laboratory, to advance research in cancer detection and treatment technologies. Dr. Korangath will...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded a $679,290 Project Grant to the University of California, San Francisco (UCSF) under the Cancer Detection and Diagnosis Research Program (CFDA 93.394) to develop and translate novel hyperpolarized (HP) carbon-13 dual-agent magnetic resonance imaging (MRI) technologies for improved prostate cancer diagnosis and biopsy guidance. The award, effective April 1, 2026, through March 31, 2031, supports research designed to...
- Federal Grant Award Summary The National Cancer Institute (NCI) awarded the University of Oklahoma Health Sciences Center a $592,731 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) beginning May 15, 2026, and concluding April 30, 2031. This award supports a randomized controlled trial to improve prostate cancer screening among Black men in Oklahoma through development and validation of the Prostate Cancer Genius App (PCGA), a smartphone-based mobile health...
The National Cancer Institute (NCI) awarded a $604,616 Project Grant to The Johns Hopkins University, effective May 12, 2026 through April 30, 2031, under the Cancer Cause and Prevention Research program (CFDA 93.393). This award supports the establishment of the Prostate Cancer Cohort Consortium (PC3), a collaborative epidemiologic initiative designed to improve precision risk stratification and prevention strategies for prostate cancer. The project integrates ten major cancer epidemiology cohorts comprising 72,494 prostate cancer cases and 8,160 prostate cancer deaths, with particular focus on high-risk populations including Black men, older men, and men with significant comorbidities. Key deliverables include implementation of molecular tumor subtyping methodologies, establishment of centralized data-sharing infrastructure, development of open-source R analytical packages, and consolidation of tumor biorepositories to enable unprecedented precision in prostate cancer prevention research. The consortium will evaluate molecular biomarkers, particularly ETS fusions and PTEN loss mutations, to identify cancer subtypes with differential sensitivity to hormonal interventions and improve post-diagnosis outcomes. By pooling resources and standardized data across participating cohorts including the NIH-AARP Diet and Health Study, Agricultural Health Study, and Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, PC3 establishes foundational infrastructure for precision prevention efforts informed by tumor biology rather than clinical presentation alone, thereby addressing a significant gap in prostate cancer epidemiology research lacking prior consortium-level molecular characterization.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $604.6k | 5/13/26 |