Project Grant R01CA297821
Award Date 5/1/26
Completion Date 4/30/31
Dollars Obligated $638K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Pittsburgh, PA 15222, USA
Similar Awards
- Federal Grant Award Summary The University of Pittsburgh received a $408,829 Project Grant from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), effective September 1, 2025 through August 31, 2027. The award supports development of an integrative framework for surface protein imputation in spatial biology applications. The project will advance understanding of tumor microenvironments by creating machine learning approaches to predict surface protein...
- Federal Grant Award Summary The University of Pittsburgh received a $149,804 Project Grant from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398) awarded March 1, 2025, with completion scheduled for February 28, 2026. This award supports research investigating the impact of LAG3 (Lymphocyte Activation Gene 3) on CD8+ T cell motility and migration in the context of cancer immunotherapy. The research builds upon preliminary findings demonstrating that...
- Federal Grant Award Summary The University of Pittsburgh received a $412,856 Project Grant from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396), awarded May 1, 2026, with completion targeted for April 30, 2028. This research initiative investigates cell cycle plasticity in bladder cancer growth and progression by developing innovative single-cell spatial proteomics and machine learning methodologies to map distinct cell cycle programs across 661...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Pittsburgh $109,076 under the Cancer Research Manpower program (CFDA 93.398) on January 21, 2026, with a completion date of July 31, 2029. This project grant funds research to develop innovative computational and analytical tools for tracking metastatic breast cancer subclones and predicting therapeutic vulnerabilities. The research integrates machine learning techniques, including transformer...
- Federal Grant Award Summary The University of Pittsburgh received a $141,566 Project Grant award from the National Cancer Institute (NCI) under the Cancer Research Manpower program (CFDA 93.398), effective March 24, 2026, with completion targeted for February 28, 2028. This K99/R00 Pathway to Independence Award supports research career development focused on understanding small GTPase (SMG) regulation and function in cancer environments. The grant funds research activities aimed at developing...
- Federal Project Grant Award Summary The University of Pittsburgh received a $435,788 Project Grant from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395), effective April 1, 2026, through March 31, 2031. This award supports the development of active site-directed inhibitors and bifunctional degraders targeting mutant isocitrate dehydrogenase (IDH1 and IDH2) enzymes implicated in progressive gliomas and hematological malignancies. The research addresses a...
- Federal Grant Award Summary The University of Pittsburgh received a $408,829 Project Grant from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) effective June 1, 2025, through May 31, 2027. This award supports the development of positive allosteric modulators (PAMs) targeting XCR1, a chemokine receptor expressed on conventional dendritic cells subtype 1 (CDC1s). The research will utilize DNA-encoded library (DEL) technology and cryo-electron...
- Federal Grant Award Summary The University of Pittsburgh received a $658,492 Project Grant from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395), effective March 18, 2026, through February 28, 2031. This award supports research and development of a novel targeted combinatorial therapy for advanced castration-resistant prostate cancer (ACRPC), including castration-resistant prostate cancer adenocarcinoma (CRPC-ADENO) and neuroendocrine prostate...
- Federal Grant Award Summary The University of Pittsburgh has received a $121,857 Project Grant from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) effective August 1, 2025, through July 31, 2027. This award supports a K99/R00 Pathway to Independence research project investigating how anti-cancer drugs modulate T cell activity within the tumor microenvironment to overcome immune checkpoint blockade (ICB) resistance. The research delivers three integrated...
- Federal Grant Award Summary The University of Pittsburgh received a $261,662 Project Grant award from the National Cancer Institute under the Cancer Research Manpower program (CFDA 93.398) effective December 1, 2025, through April 16, 2029. This grant supports an integrated in silico and in vivo genetic screening research project designed to identify subtype-specific therapeutic dependencies in hepatocellular carcinoma (HCC). The project delivers advanced computational and experimental...