The National Cancer Institute (NCI) awarded a $619,294 Project Grant under CFDA 93.394 "Cancer Detection and Diagnosis Research" to the University of California, San Diego (UCSD) to develop slow-release CPMV (Cowpea Mosaic Virus)-polymer blend formulations for intratumoral immunotherapy delivery. The project aims to formulate CPMV-laden slow-release devices, establish and tune the release rates, confirm the structural integrity and biological activity of the released CPMV, and perform preclinical and clinical testing to establish the efficacy, mechanism of action, and safety as a function of dose and delivery device, focusing on metastatic breast cancer models. The award will fund this research over a 5-year period from Aug 1, 2024 to Jul 31, 2029.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $619.3k | 7/18/24 |