This Project Grant award from the National Cancer Institute (NCI), under the Cancer Treatment Research program (CFDA 93.395), provides $607,580 to The Regents of the University of California, San Francisco (UCSF) to conduct research aimed at identifying and exploiting molecular abnormalities in tumor vasculature. The goals of the 5-year project are to: 1) Identify molecular markers that distinguish tumor vasculature from normal vasculature, 2) Determine if inhibiting the marker ENPEP can improve outcomes in glioblastoma models, and 3) Develop and validate novel antibodies targeting cell-surface markers of tumor vasculature. This research is expected to lead to the identification of optimal biomarkers for tumor vasculature and the development of new therapeutic approaches for targeting the tumor microenvironment, with potential applications in cancer diagnostics and treatments.
Generated 3/25/25, 5:17 AM