Project Grant R01CA292100
- Federal Grant Award Summary The National Cancer Institute awarded the University of Illinois a $386,279 Project Grant on July 10, 2025, under the Cancer Detection and Diagnosis Research program (CFDA 93.394) to develop innovative immunotherapy screening capabilities. The grant funds the creation of a microfluidic device cassette and associated functional immune assay protocols designed to enable personalized immunotherapy screening directly on core needle biopsies from cancer patients. This...
- Federal Project Grant Award Summary The National Cancer Institute (NCI) awarded the University of Miami's Office of Research Administration within the School of Medicine a Project Grant totaling $109,076.00 under the Cancer Research Manpower program (CFDA 93.398) on December 17, 2025. The award supports biomedical research training and career development initiatives focused on cancer research through September 1, 2029. This project grant funds the institution's capacity to provide integrated...
- Summary of Federal Project Grant Award The University of Illinois at Urbana-Champaign received a $1,477,345 Project Grant award from the National Cancer Institute (NCI) under the Cancer Centers Support Grants program (CFDA 93.397), effective April 1, 2026 through March 31, 2029. This award supports the Cancer Center at Illinois (CCIL), which provides organizational infrastructure and coordination for high-quality, interdisciplinary cancer research. The center delivers research services through...
- Federal Grant Award Summary The University of Chicago received a $372,628 Project Grant from the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394) effective September 12, 2025, through August 31, 2028. This award supports the development and advancement of spatiomolecular profiling technologies for cancer research, specifically building upon the institution's Array-Seq large-format spatially resolved transcriptomics (ST) platform. The project...
- Federal Grant Award Summary The National Cancer Institute awarded a $404,972 Project Grant to The University of Texas Health Science Center at San Antonio under the Cancer Biology Research program (CFDA 93.396) for a two-year project period beginning August 1, 2025 and concluding July 31, 2027. This award supports fundamental research investigating ribosomal ribonucleic acid (rRNA) modification, ribosome composition, and specialized translation mechanisms in glioblastoma, the most common and...
- Federal Grant Award Summary The University of Texas MD Anderson Cancer Center received a $432,134 Project Grant award from the National Cancer Institute (NCI) under the Cancer Treatment Research program (CFDA 93.395) on June 5, 2025, with a completion date of May 31, 2027. This grant funds research into IL13RA2-targeted radioimmunotherapy (RIT) for glioblastoma, an aggressive primary brain tumor with poor prognosis. The research focuses on developing and evaluating therapeutic approaches that...
- Federal Grant Award Summary The University of Chicago received a $361,807 Project Grant award from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) on June 1, 2025, with a completion date of May 31, 2028. This planning grant (R34) supports the tailoring and refinement of an engaging technology-assisted cognitive behavioral therapy (TCBT) intervention called MYTH for adolescents and young adults (AYA) diagnosed with hematological malignancies. The award...
- Federal Project Grant Award Summary Purdue University received a $437,654 Project Grant award from the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396) on March 19, 2026, with a completion date of February 28, 2031. The research project, "Dissecting the Role of Tumor Suppressing microRNAs in Angiosarcoma," aims to identify and characterize tumor-suppressing microRNAs (miRNAs) that prevent angiosarcoma development in endothelial cells. The project...
- Federal Grant Award Summary The University of Illinois received a $573,470 Project Grant award from the National Cancer Institute (NCI) under the Cancer Detection and Diagnosis Research program (CFDA 93.394), with an award date of August 25, 2025, and completion date of July 31, 2030. The grant supports the development of Resonance Enhanced Null-Deflection Infrared (RENDIR) Spectroscopic Imaging, an advanced atomic force microscopy-infrared (AFM-IR) technology platform designed to enable...
- Federal Grant Award Summary The National Cancer Institute awarded a $646,881 Project Grant to the Regents of the University of Michigan (Office of Research and Sponsored Projects) under the Cancer Treatment Research program (CFDA 93.395) for the period April 1, 2026, through March 31, 2031. This research project focuses on developing and evaluating small molecule inhibitors targeting ASH1L (Absent, Small or Homeotic 1-Like), a histone methyltransferase protein implicated in acute leukemia...
The University of Illinois received a $544,520 Project Grant award from the National Cancer Institute under the Cancer Treatment Research program (CFDA 93.395) on April 7, 2026, for the development of a microRNA (miRNA)-based therapeutic approach targeting pediatric high-grade gliomas (PHGGs). The project, scheduled for completion by March 31, 2031, aims to develop a tumor-targeting therapeutic agent specifically designed for PHGGs on a molecular basis. The research focuses on addressing the oncogenic overexpression of mir20a in pediatric glioblastomas and diffuse intrinsic pontine gliomas by creating a cell-penetrating peptide-conjugated antisense-mir20a therapeutic (AMIR20-P28) that preferentially accumulates at tumor lesions in the brain and induces apoptotic cell death. This targeted approach addresses the critical unmet clinical need for effective chemotherapy options in pediatric high-grade gliomas, which remain the leading cause of cancer-related mortality in children and adolescents despite current multimodal treatment strategies. The project delivers research and development services centered on translational cancer therapeutics, encompassing molecular characterization of miRNA expression profiles, design and optimization of cell-penetrating peptide delivery systems, and preclinical evaluation of therapeutic efficacy. The research will be conducted at the University of Illinois Chicago campus and is expected to generate intellectual property and scientific publications advancing understanding of miRNA-based cancer therapeutics applicable to lethal pediatric brain malignancies with poor prognosis.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $544.5k | 4/9/26 |