Project Grant R34CA297498

Award Date 6/1/25
Completion Date 5/31/28
Dollars Obligated $362K
Federal Grant Program
93.395
Assistance Type
Project Grant
Place of Performance
Illinois, USA
Similar Awards
This federal Project Grant award of $1,312,000.00 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports the adaptation of an inhaled substance use intervention for adolescent and young adult cancer survivors. The award to the University of Chicago will be used to develop and evaluate this novel therapeutic approach over the 4-year performance period from August 2025 to July 2029. The University of Chicago, a renowned private research...
This Project Grant award from the National Cancer Institute (CFDA 93.398 - Cancer Research Manpower) provides $161,432 to The University of Texas MD Anderson Cancer Center to develop and evaluate a virtual, group-based expressive writing intervention for adolescent and young adult cancer survivors (AYACSS). The overarching goal is to enhance the quality of life and reduce stress among this population, who face multiple psychosocial disparities. The award will fund a 2-year research plan with the...
The National Cancer Institute (NCI) awarded a $664,259 Project Grant under the Cancer Cause and Prevention Research (CFDA 93.393) program to Duke University. The grant is for the development and evaluation of the "AYA STEPS" digital health intervention, which aims to help adolescent and young adult (AYA) cancer survivors manage their symptoms and improve engagement with post-treatment care. The project involves a randomized controlled trial to assess the efficacy of the AYA STEPS...
This $290,052 Project Grant award from the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research program (CFDA 93.393) supports the development and evaluation of a mobile-optimized intervention called PERCS-YA (Personalized Cancer Support for Young Adults) to reduce worry and distress among young adult cancer survivors. The award will fund stakeholder-engaged refinement of the PERCS-YA intervention, followed by a Phase II efficacy trial utilizing both a...
This Project Grant award of $922,186 from the National Institute of Nursing Research (NINR, CFDA 93.361 Nursing Research) aims to develop and pilot test a digital intervention called AYA-NAV that addresses financial toxicity and unmet health-related social needs among adolescent and young adult (AYA) cancer survivors. The intervention will leverage the FindHelp.org digital network and a clinical vocational liaison team to provide navigation services to AYAs struggling with issues like food...
This $377,870 Project Grant awarded by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) supports the development and validation of novel synthetic transcriptional repressors (STRs) capable of directly inhibiting the oncogenic transcription factor MYC. The grant aims to: 1) Optimize STR structures for high-affinity and specific binding to MYC target DNA sequences, 2) Enhance cellular and pharmacologic delivery of STRs while mapping their effects on epigenetic and...
This Project Grant award of $621,732 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports research to evaluate a proactive identification and digital mental health intervention approach to address the unmet psychosocial needs of individuals living with likely incurable cancer. The key products or services to be delivered through this 5-year grant include: 1) Comprehensively assessing the effectiveness of a proactive identification method paired with...
The National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) awarded a $300,924 Project Grant to the Regents of the University of Michigan to determine the feasibility of implementing a randomized controlled trial of an 8-week, virtually-delivered, tailored music-based relaxation (TIMBRE) intervention to reduce anxiety in adolescent and young adult (AYA) cancer survivors. The primary aim is to assess the feasibility of the TIMBRE intervention, with secondary goals of evaluating the...
The University of Chicago was awarded a $1,306,778 Project Grant by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) federal grant program. The grant supports advanced biomedical research focused on "Immunologic Drivers of Lineage Bias in TP53-Mutant Acute Leukemia". The research aims to transform healthcare for military service members and the broader public through innovative, impactful investigations across medical disciplines. The 4-year...
This Project Grant award for $166,984 from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) supports efforts to increase enrollment of adolescent and young adult (AYA) cancer patients on clinical trials at the Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins University. The project will develop and implement an "AYA: ALERT, Young Adult Navigation, Alliance" system to identify eligible AYA patients, provide them with timely information about...

The University of Chicago was awarded a $361,807 Project Grant by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to tailor a technology-assisted cognitive behavioral therapy (TCBT) program for adolescents and young adults (AYAs) with hematological malignancies.

The objectives of this 3-year grant are to: 1) Collaborate with an advisory panel of AYA cancer survivors and stakeholders to refine and tailor the existing TCBT program, called MYTH, for the specific needs of the AYA hematological malignancy population (MYTH-C); 2) Collect data to design and plan a future multi-center randomized controlled trial of MYTH-C across three study sites; and 3) Conduct a pilot randomized controlled trial to evaluate the feasibility and acceptability of delivering MYTH-C at the University of Chicago Medicine site. The goal is to develop an engaging, evidence-based mental health intervention to address the unique psychosocial challenges faced by AYAs diagnosed with hematological cancers.

Generated 7/15/25, 8:37 AM