Project Grant R01CA289268

Award Date 7/1/24
Completion Date 6/30/29
Dollars Obligated $1M
Federal Grant Program
93.393
Assistance Type
Project Grant
Place of Performance
Seattle, WA 98195, USA
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The National Cancer Institute (NCI) awarded a $1,039,794 Project Grant (CFDA 93.393 - Cancer Cause and Prevention Research) to the University of Washington (UW) to conduct the "BEST CARE FOR RECURRENT NMIBC" study. The study aims to:

  1. Compare long-term clinical and patient-reported outcomes between patients with recurrent non-muscle invasive bladder cancer (NMIBC) who undergo bladder-sparing therapy (BST) versus radical cystectomy.

  2. Determine if prediction of progression to muscle-invasive or metastatic bladder cancer can be improved by incorporating molecular staging factors.

  3. Evaluate the financial impact of newly approved BST options.

The study leverages data from the PCORI-funded CISTO cohort and will follow patients over 5 years to address critical knowledge gaps in the optimal management of recurrent high-grade NMIBC. The findings have the potential to inform clinical practice and improve patient-centered care for this common and costly form of bladder cancer.

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