Project Grant R01CA288969
- This $435,827 Project Grant from the National Cancer Institute (NCI) under the CFDA 93.394 Cancer Detection and Diagnosis Research program supports research conducted by New York University (NYU) School of Medicine to develop deep learning methods for analyzing mass spectrometry imaging (MSI) data. The goal is to make MSI data more accessible to existing machine learning workflows by expanding the dimensionality of the data structure to treat each metabolite or lipid as an individual "color...
- This Project Grant award, totaling $450,904, was provided by the National Cancer Institute (NCI) under the Cancer Biology Research federal grant program (CFDA 93.396). The grant was awarded to the Battelle Memorial Institute's Pacific Northwest National Laboratory to develop a single-cell (phospho-)proteomics platform to enable robust and rapid analysis of the tumor microenvironment at both the proteome and phosphoproteome levels. The key objectives are to address three major challenges: 1)...
- This Project Grant award, valued at $424,734 and provided by the National Cancer Institute (CFDA 93.396 - Cancer Biology Research), supports the development of a novel spatial proteomics approach to analyze the tumor microenvironment. The University of Illinois, the award recipient, will integrate 3D microscopy techniques with bottom-up proteomic assays to profile the proteomes of specific immune cells within different subregions of a mouse tumor. This innovative methodology aims to...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA 93.859 Biomedical Research and Research Training program provides funding of $258,586 to MSTM LLC to develop an advanced surface sampling and ionization technology for remote detection of molecular compositions. The goal is to demonstrate the feasibility and proof-of-concept of a "Surface Reader" device that can directly sample surfaces using a liquid meniscus or indirectly via laser...
- This $632,300 Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) aims to develop an integrated ultra-high-throughput 3D volumetric super-resolution imaging system for studying the tumor microenvironment. The project, led by Carnegie Mellon University, will combine a multiscale fluorescence mesoscope with expansion microscopy to enable rapid, large-area 3D imaging at the subcellular level. This innovative system will allow researchers to visualize...
- The National Cancer Institute (NCI) awarded a $400,000 Project Grant under CFDA 93.394 (Cancer Detection and Diagnosis Research) to O2M Technologies LLC to develop a Multifunctional Imager (MFI) that can simultaneously acquire tissue oxygen pressure (pO2) and pH maps using electron paramagnetic resonance imaging (EPRI) techniques. The 12-month project aims to create a 25 MT Halbach-type permanent magnet, new multi-modal transmit-receive electronics, and the integrated MFI instrument. This...
- This federal Project Grant award from the National Cancer Institute's Cancer Detection and Diagnosis Research program (CFDA 93.394) supports a research project titled "Ultra-Sensitive Mass Spectrometry-Based Immunopeptidomics Using Digital Microfluidics" at Yale University. The $672,371 award aims to develop advanced mass spectrometry-based techniques to precisely and sensitively identify tumor-specific antigens (TSAs) from small tissue samples. This research is critical for...
- The federal Project Grant award of $306,872 from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) supports the development of a new "Multi-Camera Array Scanner" (MCAS) imaging system by Ramona Optics Inc. The MCAS is designed to rapidly digitize and automatically analyze 3D fine-needle aspiration cytology slides, which are a critical first step in the cancer diagnosis pipeline. This technology aims to enable real-time assessment of specimen adequacy and provide...
- This Project Grant award of $418,176 from the National Cancer Institute (NCI), under the Cancer Biology Research federal grant program (CFDA 93.396), is supporting the continued advanced development and validation of nucleic acid cytometry technology at the Sloan-Kettering Institute for Cancer Research. The goal is to enable the programmable enrichment and profiling of rare cell populations from tumor and tissue samples, overcoming limitations of current antibody-based cell sorting methods....
- This $449,726 federal Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) supports the development of innovative tools to enable the rapid, high-sensitivity mapping of changes in protein interactions within living cells. The University of Illinois is the primary awardee and will leverage advanced biotinylation techniques, including light-regulated and engineered biotin ligases, to facilitate the real-time analysis of dynamic changes in protein...
This federal Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $465,028 to North Carolina State University to advance functional mass spectrometry imaging (FMSI) methodology. The goal is to develop FMSI as a unique bioanalytical tool that can provide high spatially-resolved functional data on tissue perfusion, metabolic activities, and other dynamic physiological processes in any tissue sample. The key products and services to be delivered under this 5-year award include: Successful completion of these aims will position the FMSI approach as a powerful tool to provide high-resolution functional data on dynamic physiological processes in various tissue types.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $465.0k | 12/13/24 |