Project Grant R33CA287139
Award Date 9/1/25
Completion Date 8/31/28
Dollars Obligated $451K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Washington, USA
Similar Awards
- This federal Project Grant award of $418,176 from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) supports the development and validation of a novel approach called "Programmable Nucleic Acid Cytometry" at the Sloan-Kettering Institute for Cancer Research. The project aims to advance this innovative method for profiling rare cell populations from tumors and tissues, which offers advantages over traditional antibody-based cell isolation techniques. The work will...
- The Project Grant award of $424,734 from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) supports the development of a novel spatial proteomics approach to profile immune cell types and their locations within a tumor microenvironment. The University of Illinois, the awardee, aims to integrate 3D microscopy techniques with bottom-up proteomic assays to offer deep proteome profiles of specific immune cells at various subregions of a mouse tumor (Aims 1 and 2). The goal is...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under CFDA program 93.859 Biomedical Research and Research Training provides $350,000 to Fluidispec LLC to develop a new microfluidic/nanofluidic sample preparation platform. The goal is to improve single-cell and low-input proteomics analysis by enabling efficient extraction of proteins from cells, removal of contaminants, and improved protein denaturation. This platform is expected to enhance...
- This $671,072 federal Project Grant award from the National Cancer Institute (CFDA 93.394 - Cancer Detection and Diagnosis Research) will fund the development of a novel microdevice to measure malignant lipid signaling in single cells from clinical samples. The University of Washington will lead a multidisciplinary collaboration to create a "picoliter thin-layer chromatography" (PTLC) chip and supporting hardware, integrating bioengineering, chemistry, and oncology expertise. This...
- This federal Project Grant award, valued at $401,829.00 and awarded by the National Cancer Institute under the Cancer Biology Research program (CFDA 93.396), supports innovative research by Weill Medical College of Cornell University to develop transformative methods for high-throughput single-cell mapping of DNA-binding proteins. The project, titled "Precision Single-Cell Mapping of Chromatin-Associated Protein Activity by Molecular Footprinting to Chart Disruptions to Gene Regulation...
- This $204,027 federal Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) is supporting the Weill Medical College of Cornell University in expanding single-cell and spatial technologies to link clonal genotypes with phenotypes during cancer evolution. The grant aims to develop advanced single-cell methods that can capture multiple data modalities, including genotypes, transcriptomes, methylomes, and protein expression, to better understand how somatic...
- This $302,671 federal Project Grant awarded on August 2, 2025 by the National Institute of General Medical Sciences (CFDA 93.859 Biomedical Research and Research Training program) to Andson Biotech Inc. aims to develop an innovative real-time mass spectrometry platform for in-process monitoring and cell state analysis of advanced cell therapies. The project seeks to address the challenges of variable quality and efficacy in cell therapies by enabling real-time measurement and control of critical...
- This federal Project Grant award of $465,197 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a next-generation lipidomics platform using advanced mass spectrometry and bioinformatics technologies. The goal is to enable high-throughput lipidomic profiling with high structural specificity to unravel the relationship between lipids and their associated functions in biological...
- This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) to Pumpkinseed Technologies Inc. for $353,204 supports the development and demonstration of a novel technology called Cell-MAPP. The goal of this Phase I SBIR project is to create the first system capable of continuously monitoring the state transitions of individual T cells in response to antigen exposure. Cell-MAPP will utilize antigen-multimer barcoding and single-cell TCR sequencing to connect...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
This Project Grant award for $450,904 from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) will support the development of a single-cell (phospho-)proteomics platform at the Pacific Northwest National Laboratory, operated by Battelle Memorial Institute. The platform aims to address key challenges in single-cell proteomics analysis, including low recovery for phospho-enrichment, insufficient mass spectrometry sensitivity, and low sample throughput. This new platform will enable robust, rapid analysis of single cells at both the proteome and phosphoproteome levels, providing complementary data to enhance understanding of the tumor microenvironment and support progress towards precision medicine.
Generated 10/21/25, 5:12 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.9k | 8/8/25 |