Project Grant R01CA278776
- This $723,676 federal Project Grant award was provided by the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) to Wake Forest University Health Sciences (WFUHS) to conduct research on the long-term effects of electronic cigarettes on brain health. The research project aims to investigate the comparative impacts of smoking cessation versus switching from traditional cigarettes to e-cigarettes on measures such as gray matter volume, white matter...
- The federal Project Grant award titled "Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit" is funded by the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) for $663,554.00 with an award date of August 18, 2025 and an ultimate completion date of July 31, 2030. The grant supports research to explore the use of harm reduction product sampling, such as e-cigarettes, heated tobacco products, and oral...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $265,239 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the University of North Carolina at Chapel Hill (UNC-CH) to investigate the effects of vaping-induced oxidation on nicotine analogs in e-cigarettes. The project aims to evaluate the chemical composition of 6-methyl nicotine and nicotinamide vaping products before and after aerosolization, and assess...
- The University of Pittsburgh received a $2,202,321 Project Grant from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to conduct an experimental investigation on the impact of dyadic processes on smoking and cigarette craving. The 4-year project, running from August 2025 to July 2029, will examine how social factors, particularly romantic partner and friend dynamics, influence smoking behaviors and craving in an effort to develop a more comprehensive...
- This federal Project Grant award of $619,175 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports a Type 1 hybrid effectiveness-implementation trial to evaluate a novel harm reduction approach for oncology outpatients who smoke but refuse traditional tobacco treatment. The study will directly compare rates of switching from cigarettes to e-cigarettes against standard care, while also assessing key barriers and facilitators to implementation. The...
- This Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) is providing $931,766 to West Virginia University to evaluate dependence and nicotine replacement therapy-supported cessation efforts among regular electronic cigarette (e-cigarette) users. The project aims to assess unique indicators of e-cigarette dependence in individuals who have never been established cigarette smokers or have transitioned from cigarette smoking to...
- This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) provides $687,995.00 to Yale University to conduct a randomized clinical trial investigating the efficacy of varenicline (Chantix) for cessation of electronic cigarette (e-cigarette) use in adults. The study aims to test the hypothesis that varenicline is an effective intervention for helping e-cigarette users quit, given the addictive nature of nicotine in e-cigarettes and...
- The National Cancer Institute (NCI) awarded a $399,891 Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) to Sensewhy, Inc. (UEI: N7FTT2U8NHX7) to evaluate the feasibility and clinical utility of the "Smokemon" wearable device for detecting smoking topography and predicting smoking lapses among cancer survivors who are daily smokers. The project will involve a one-week pre-quit observation period and a four-week post-quit observation period, during which...
- This Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) aims to develop machine learning approaches to personalize cigarette smoking risk prediction for adults trying to quit smoking. The $200,676 award supports research to identify dynamic patterns and key features that predict smoking lapses and relapses during quit attempts, in order to inform the development of personalized smoking cessation interventions and clinical...
- This $105,076 Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to investigate the neurocomputational basis of effort-based decision making (EBDM) in individuals with tobacco use disorder, tobacco and opioid use disorder, and healthy controls. The award will support research to characterize the neurocomputational basis of EBDM during a smoking cessation attempt. The project will computationally model...
The University of Alabama was awarded a $2,524,071 Project Grant by the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research) on September 23, 2025. The grant supports a research project to investigate the neural mechanisms that underlie self-regulation and reinforcement learning in smoking decisions among e-cigarette or other electronic nicotine delivery system users. The study will use computational modeling, multi-modal neuroimaging (EEG, fMRI), and custom-made smoking devices to examine how interoceptive, affective, and cognitive control networks influence smoking urges and behaviors, both in the short-term (trial-by-trial) and long-term (over one year). The ultimate goal is to provide insights that could help prevent self-control failures and improve smoking cessation outcomes. The project is expected to be completed by August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 9/22/25 |