Project Grant R01CA302758
- This federal Project Grant award of $619,175 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) supports a Type 1 hybrid effectiveness-implementation trial to evaluate a novel harm reduction approach for oncology outpatients who smoke but refuse traditional tobacco treatment. The study will directly compare rates of switching from cigarettes to e-cigarettes against standard care, while also assessing key barriers and facilitators to implementation. The...
- The National Cancer Institute (NCI) awarded a Project Grant under the Cancer Cause and Prevention Research program (CFDA 93.393) to the University of Oklahoma Health Sciences Center to conduct a randomized factorial trial on smoking cessation interventions. The $625,201 award, effective January 1, 2025 through December 31, 2029, will evaluate the combined impact of varenicline medication plus nicotine lozenges, and a smartphone-based medication adherence intervention, on 7-day point prevalence...
- This Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) to Yale University for $687,995.00 will fund a 5-year randomized clinical trial to investigate the efficacy of varenicline for cessation of e-cigarette use in adults. The study will enroll 326 treatment-seeking participants who use e-cigarettes exclusively, with and without a history of cigarette smoking, to evaluate whether varenicline can help them quit e-cigarettes compared to a...
- This $515,632 federal Project Grant was awarded on May 2, 2025 by the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393). The grant supports research to prepare the nation and states for potential U.S. Food and Drug Administration (FDA) cigarette product standards, including a proposed menthol ban and nicotine reduction standard. The overarching objective is to ensure the U.S. is fully prepared to maximize smoking cessation during and...
- This Project Grant award of $395,248 was provided by the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), to Virginia Polytechnic Institute & State University (Virginia Tech) from August 2025 to July 2027. The project aims to develop and test the feasibility of using "episodic future thinking" interventions to help cigarette smokers quit by increasing their valuation of future health outcomes, such as avoiding cancer. The...
- This Project Grant award for $693,491 was provided by the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279). The award will fund a mixed-methods longitudinal study to advance the scientific understanding of nicotine pouch use patterns among U.S. adults, including those who use other tobacco products. The study will employ a nationally representative survey integrated with qualitative interviews to answer key questions about who is using...
- This Project Grant award for $265,239 was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports research to evaluate the chemical composition and toxicity of e-cigarette aerosols containing 6-methyl nicotine and nicotinamide. Specifically, the project aims to analyze the chemical changes that occur when these nicotine analogs are aerosolized and assess their toxicity in human bronchial epithelial cells. This...
- This federal Project Grant award of $757,913 from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) will fund research to enhance the efficacy of a smoking cessation smartphone app for Hispanic adults. The grant will be used to provide nicotine replacement therapy in conjunction with the 'iCanQuit' app, which has demonstrated efficacy for smoking cessation in prior trials. The research aims to improve access to evidence-based smoking cessation interventions for...
- This federal Project Grant award of $931,766.00, awarded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research on evaluating electronic cigarette (ECIG) dependence and the efficacy of nicotine replacement therapy (NRT) for ECIG cessation among non-smoking ECIG users. The key objectives are to: 1) assess if non-smoking ECIG users experience unique indicators of ECIG dependence compared to existing measures developed...
- This federal Project Grant award from the National Cancer Institute (NCI), under the Cancer Cause and Prevention Research program (CFDA 93.393), provides $906,306 to Duke University to develop and pilot test a telehealth-delivered, cue-based smoking cessation intervention for people who smoke lightly (10 cigarettes per day or less). The primary objectives are to: 1) adapt a previously tested cue-based smoking cessation intervention to a telehealth format, and 2) conduct a two-arm randomized...
The Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) is providing $663,554 to The Trustees of the University of Pennsylvania to conduct research focused on catalyzing smoking cessation through harm reduction product sampling among people unmotivated to quit smoking. The research aims to evaluate the impact of providing people who smoke with a choice of alternative nicotine products, including e-cigarettes, heated tobacco products, and oral nicotine pouches, as a pragmatic approach to transitioning them away from combustible cigarettes. The award has an initial period of performance from Aug 18, 2025 to Jul 31, 2030 and seeks to disrupt decades of smoking and toxicant exposure, thereby reducing smoking-attributable morbidity and mortality.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $663.6k | 8/18/25 |