Project Grant R01AT013724
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $391,364 Project Grant to the University of California, Davis (UC Davis). The grant, with a performance period from September 4, 2025 to August 31, 2030, aims to characterize the vitamin B metabolism pathways in parasitic nematodes and their hosts. The project seeks to identify which vitamin B components the nematodes obtain from their hosts versus...
- The Department of Health and Human Services National Institutes of Health (NIH) awarded a $1,516,500 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to Harvard University's Office for Sponsored Programs Division. The grant, effective from September 1, 2025 to August 31, 2028, supports research to develop organic, metal-free catalysts capable of performing chemical processes traditionally enabled by transition metals. The goal is to discover strategies that use entire...
- This $878,400 project grant from the Department of Health and Human Services National Institutes of Health National Cancer Institute Cancer Biology Research program (CFDA 93.396) will fund research characterizing vitamin B6 pathway dependency in acute myeloid leukemia (AML) at Cold Spring Harbor Laboratory from January 2023 through December 2027. The research aims to further the understanding of the underlying mechanisms of AML by studying abnormal vitamin pathways and metabolic programming...
- This Project Grant award from the National Institute on Aging (NIA) under CFDA 93.866 - Aging Research will provide $314,000.00 over the period of May 1, 2025 to April 30, 2027 to the University of California, Irvine (UCI) to conduct research on the "Molecular Mechanisms Underlying Reduced Vitamin C Transport Process in Alzheimer's Disease and its Impact on Neuroinflammation". The project aims to investigate the underlying causes for vitamin C deficiency observed in Alzheimer's disease...
- This Project Grant award, with a total of $1,476,000.00 funded by the Department of Health and Human Services National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support), supports research to engineer enhanced erythropoiesis (red blood cell production) for treating red blood cell disorders. The project aims to develop a novel approach that uses genome engineering to increase production of desired cell types and lower the therapeutic editing threshold, as an alternative to current ex...
- This $156,000 Project Grant award from the National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) will support research on the "Effects of Earlier and Higher Vitamin D Supplementation in Extremely Preterm Newborns at 2 Years of Age". The award period runs from September 1, 2025 to August 31, 2027 and will be conducted by the University of Texas Health Science Center at Houston (UTHealth). This grant is funded under NCATS' mission to...
- The federal Project Grant award of $731,827 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) is supporting research conducted by the J. David Gladstone Institutes in San Francisco, CA to investigate the mechanisms of oxygen toxicity. The key objectives include: 1) testing whether specific molecular pathways (diphthamide synthesis, de novo purine synthesis, and mitochondrial electron transport chain) are necessary and sufficient for impaired cell...
- The federal Project Grant award DP2GM154152, in the amount of $1,525,500.00, was provided by the National Institutes of Health (NIH) through the Trans-NIH Research Support program (CFDA 93.310). The award will support a project at Harvard Medical School to develop experimental and analytical approaches for capturing and quantifying "chemical epistasis" - the combinatorial effects of different small molecules in biological signaling and processes. The project aims to advance the...
- The U.S. Department of Health and Human Services, National Institutes of Health (NIH) awarded a $878,991 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to a collaborative research partnership between Henry Ford Health and Michigan State University Health Sciences. The award period is from September 10, 2025 to August 31, 2030. The project aims to develop "I/O tags" - genetically encoded proteins that can achieve targeted trans-neuronal delivery to...
- This Project Grant award, valued at $574,000.00, was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to The Regents of the University of California, San Francisco (UCSF). The grant supports advanced biomedical research aimed at transforming healthcare for military service members, veterans, and the broader public. Specifically, this award will fund research to develop innovative methods for targeting and imaging vitamin B5...
This Project Grant award from the Department of Health and Human Services' National Institutes of Health (CFDA 93.310 - Trans-NIH Research Support) provides $1,321,208 to the J. David Gladstone Institutes to conduct research to "fundamentally transform the field of vitamin biology." The key objectives are to systematically identify vitamin-dependent enzymes and metabolic pathways, explore the body's ability to sense and respond to vitamin levels, and investigate the potential of "megavitamin therapies" for genetic disorders. The research project aims to develop new sensors, pathways, and precision therapies related to vitamins and their role in health and disease. This 5-year project, which commenced on August 14, 2025, builds on the organization's prior work demonstrating the therapeutic potential of high-dose vitamin B3 for the genetic disorder NAXD.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/14/25 | ||
| Not listed | $1.3m | 8/12/25 |