This federal Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health (CFDA 93.213) program, provides $125,026 to the Massachusetts Institute of Technology (MIT) to conduct research on the brain bases of mindfulness. The project aims to: 1) identify brain network connections that predict trait mindfulness using resting-state fMRI data, and 2) examine state mindfulness and its...
The National Institutes of Health National Center for Complementary and Integrative Health awarded New York University $785,637 under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) from June 2021 through May 2025. This Cooperative Agreement will support the development and pilot testing of telephone-delivered and video-based Mindfulness-Based Cognitive Therapy (MBCT) protocols for patients with migraine headaches and depressive symptoms. Specifically, the...
This $432,300 Project Grant awarded by the National Center for Complementary and Integrative Health (NCCIH) under CFDA Program 93.213 "Research and Training in Complementary and Integrative Health" supports a multi-site pilot randomized controlled trial to evaluate the feasibility and acceptability of a mindfulness-based intervention (MBI) with a multi-modal adaptive supplement called "Learning to Breathe Plus" (L2B Plus). The project aims to prepare for a future larger-scale...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health grant program (CFDA 93.213), will fund the development and pilot testing of a novel, daily, digitally delivered mindfulness-based intervention for depressive symptoms in post-treatment cancer patients. The $165,240 award, granted to the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University,...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund a feasibility clinical trial to develop and evaluate a Psilocybin-Assisted Cognitive Behavioral Therapy (PA-CBT) protocol for treating major depressive disorder. The $236,250 award, granted on December 17, 2024, supports a 3-year study to refine and optimize the PA-CBT approach, and...
The National Center for Complementary and Integrative Health (NCCIH), under CFDA 93.213 "Research and Training in Complementary and Integrative Health", awarded a $1,415,556 Project Grant (Award ID: R01AT012238) to Butler Hospital, a division of Care New England Health System, to conduct a two-phase multi-site feasibility trial of a yoga-based intervention (YBI) for reducing depression in adolescents. The project aims to increase accessibility and feasibility of the YBI for diverse...
The National Center for Complementary and Integrative Health (NCCIH), part of the National Institutes of Health, awarded a $708,327 Project Grant (CFDA 93.213 - Research and Training in Complementary and Integrative Health) to the University of Illinois. The grant, titled "CRCNS: MULTIMODAL NETWORK INTERACTIONS FOR INTERNAL STATE DYNAMICS OF RESILIENCY", will fund research to unravel the complex mechanisms underlying individual resilience to stress. The research will utilize a...
This federal Project Grant award of $780,698 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to optimize the integration of human and digital support in a meditation app for depression and anxiety. The key products and services to be delivered include: The proposed study will conduct a hybrid factorial and micro-randomized trial to evaluate the effects of introductory coaching, on-demand email-based coaching, and digital...
This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal grant program "Research and Training in Complementary and Integrative Health" (CFDA 93.213), provides $1,283,558 to the University of Utah to evaluate the use of bioenergetic supplements like creatine and acetyl-L carnitine as potential treatments for treatment-resistant depression, cognitive dysfunction, and anxiety. The project aims to investigate how these...
This Project Grant award of $458,177 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund research to leverage population-level data to inform prevention and treatment of adolescent depression following adverse childhood experiences (ACEs). The research aims to identify combinations of factors that most affect the association between ACEs and adolescent depression symptoms, using data from the Longitudinal Adolescent Brain...
This federal Project Grant award of $731,961 from the National Center for Complementary and Integrative Health (NCCIH), under CFDA program 93.213 "Research and Training in Complementary and Integrative Health", will fund an 8-week, double-blind, placebo-controlled, multi-arm clinical trial at the University of Cincinnati. The study aims to investigate the neurobiological effects of N-acetylcysteine (NAC) and mindfulness-based cognitive therapy (MBCT) for treating mild depression in youth aged 15-24. Key objectives include determining changes in prefrontal glutamate levels and functional connectivity within prefrontal-limbic circuits and large-scale brain networks in response to the interventions. The study will also explore the role of biomarkers related to oxidative stress and inflammation in predicting treatment response. The award period is from April 2025 through March 2030.