Project Grant R01AT013058

Award Date 5/1/25
Completion Date 4/30/30
Dollars Obligated $721K
Federal Grant Program
93.213
Assistance Type
Project Grant
Place of Performance
Pennsylvania, USA
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The study aims to evaluate the neural signatures of experimental stimulation and modulation of brain network connectivity following auriculotherapy treatment, using functional near-infrared spectroscopy (fNIRS) and resting-state functional MRI. The project will include a randomized, double-blind, sham-controlled clinical trial in chronic low back pain patients to test the hypothesis that low-back auricular points are sensitized or pathologically imbalanced, and that auriculotherapy can resolve this pathologic imbalance. The findings are expected to provide mechanistic neuroscientific insights that could increase the adoption of auriculotherapy for improved pain relief and mood in chronic low back pain patients, while reducing reliance on opioids.

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