Project Grant R01AR085047
Award Date 8/22/25
Completion Date 6/30/30
Dollars Obligated $435K
Awardee
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Cleveland, OH 44195, USA
Similar Awards
- This $540,974 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to investigate the role of JAK signaling in post-traumatic osteoarthritis (PTOA)-associated cartilage degeneration and pain. The research team at Duke University will use genetic and pharmacological approaches to identify specific JAK molecules that mediate the catabolic...
- This federal Project Grant award of $487,652.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to elucidate the effects of blood and blood-derived components on meniscus tissue homeostasis, repair, and post-traumatic osteoarthritis (PTOA) development. The research will be conducted by Duke University, a leading private research institution, with the goal of...
- This federal Project Grant award of $196,460.00 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) will fund research into neuroimmune interactions and osteoarthritis pain. The University of Pittsburgh will use a novel microphysiological system to study the influence of inflammatory molecules from synovial-like tissue on innervating neurons, the role of chemokines like CXCL-1...
- This federal Project Grant award, totaling $691,089, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research to investigate the role of mechanosensing and mechanotransduction in joint homeostasis and osteoarthritis susceptibility. The University of Utah will conduct single channel biophysical analyses, cellular and molecular studies using...
- This $749,343 Project Grant awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) supports advanced biomedical research at New York University (NYU) School of Medicine to develop a peptide treatment for cartilage injuries and post-traumatic osteoarthritis. The grant, awarded on August 1, 2025, will fund this research project over a 2-year period with a final completion date of July 31, 2027. As a prominent academic medical center, NYU...
- This $322,800 federal Project Grant award was provided by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420). The grant supports research conducted by Mayo Clinic to investigate the role of osteoprotegerin as a mediator of post-traumatic osteoarthritis through a novel etiopathophysiological mechanism. The research project aims to advance scientific understanding and develop new treatments for this condition, which is particularly relevant for...
- This federal Project Grant award for $169,344.00, provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), aims to investigate the role of inflammation and immunomodulation in fracture healing for polytrauma patients. The primary objectives are to: 1) Characterize the upregulation of inflammatory cytokines and innate immune cells both systemically and locally at the...
- The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $426,889 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to the University of Southern California (USC) to investigate the molecular regulatory mechanisms of a cartilage-enriched G protein-coupled receptor (GPCR) named ADGRG6 in maintaining joint cartilage and preventing osteoarthritis (OA). The research aims to elucidate the role of ADGRG6 in...
- This $1,948,116 federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research on the post-transcriptional regulation of gene expression during bone regeneration. The research, conducted by Pennsylvania State University's Milton S. Hershey Medical Center, aims to characterize the expression and biological functions of the protein Proteoglycan...
- This $628,174 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research to investigate the cellular origins and molecular mechanisms underlying arthrofibrosis, a debilitating fibrotic joint disorder. The research aims to address critical gaps in the understanding of arthrofibrosis pathogenesis, with the goal of developing new non-surgical,...