This federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), aims to develop a novel therapeutic approach to improve angiogenesis and wound healing by delivering apoptotic neutrophils within a degradable hydrogel scaffold. The $172,700 award, effective August 20, 2024 through July 31, 2026, supports research to investigate the effects of the hydrogel-apoptotic neutrophil delivery on macrophage angiogenic signaling and its impact...
This Project Grant award of $649,391, awarded on May 12, 2025 by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), supports research to enhance healing after injury. The research, conducted by The Johns Hopkins University, aims to define the mechanisms that restrain healing in epithelial tissues like skin and gut, with the goal of developing new therapies to improve regeneration following diverse injuries or infections. The work is funded through the NIAMS...
This Project Grant award, valued at $306,324.00, was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The project aims to decipher the myofibroblast life cycle in skin wound healing. Key objectives include creating a molecular map of the myofibroblast life cycle and investigating the role of Hippo-YAP/TAZ signaling in myofibroblast deactivation and survival. The...
This federal Project Grant award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under CFDA 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research, supports research into the roles of the epidermal integrin α3β1 in age-related changes during cutaneous wound healing. The $607,398 award to Albany Medical College will fund a two-year research project to investigate how age-related decreases in the expression and function of the α3β1 integrin on...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $404,140 to Cedars-Sinai Medical Center to investigate the role of the NLRP10 protein in regulating wound healing in cutaneous leishmaniasis. The research aims to identify the mechanisms by which NLRP10 mitigates fibroblast senescence and aids the wound repair response in the presence of...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under CFDA program 93.846 Arthritis, Musculoskeletal and Skin Diseases Research, will support research to investigate the role of extracellular vesicles in mediating communication between endothelial cells and fibroblasts during skin wound healing. The $257,310 award, with a project period from September 15, 2024 to April 15, 2027, will fund in vitro and in vivo studies to examine how...
This Project Grant award of $469,766 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) aims to develop a new technology for accelerating wound healing. The key products and services to be delivered under this award include: Conducting in-vitro cell culture studies to establish the cellular mechanisms by which nanogenerator-driven electrical stimulation (NG-ES) can enhance...
This federal Project Grant award, valued at $230,212 and provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), supports research under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The goal of the research is to investigate how the immune system, specifically dendritic epidermal T cells (DETCs), drives functional heterogeneity in skin epithelial stem cells within and across different niches. The research will shed...
This Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), will provide $401,433 from September 2023 to August 2025 to support research at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. The research aims to investigate the role of protein O-GlcNAcylation in regulating keratinocyte function and its impact on skin...
This federal Project Grant award, provided by the National Institutes of Health (NIH) under the Biomedical Research and Research Training Program (CFDA 93.859), aims to advance the understanding of how Langerhans cells (LCs) and sensory neurons interact to regulate wound healing, itch, and pain following burn injuries. The University of Miami is the primary awardee, receiving $330,025 over the period of Sep 15, 2024 to Jul 31, 2028. The key objectives of this research project are to: 1)...