Project Grant R01AI202104
- The National Institute of Allergy and Infectious Diseases awarded the University of Arizona $797,394 under Project Grant R01AI201440 on August 1, 2026, to define mechanistic pathways through which infant gut microbial metabolites affect immune responses to airway viral infection and aeroallergens, and to assess their impact on airway barrier integrity. Funding supports the Allergy and Infectious Diseases Research program (CFDA 93.855). The research builds on preliminary findings from the...
- The National Institute of Allergy and Infectious Diseases awarded The Regents of the University of California, San Francisco $205,000 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate synergistic effects of dietary interventions and probiotics on gut-lung immune modulation. The project explores how fiber-rich diet combined with intermittent fasting and probiotic strategies can attenuate sterile lung injury. Research Aim 1 tests...
- The National Institute of Allergy and Infectious Diseases awarded the University of Wisconsin–Madison $1,650,321 on August 6, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct longitudinal research on early life epithelial development and asthma risk through the Childhood Allergy and the Neonatal Environment (CANOE) study. The award funds analysis of serial nasal cell samples collected from study participants beginning at birth through age 5 years to...
- The National Institute of Allergy and Infectious Diseases awarded the University of Arizona $806,740 on August 12, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to characterize the mechanisms by which natural environmental agents from traditional Amish farms protect the lungs against rhinovirus infection and associated asthma development in children. The research investigates how early-life exposure to cow barn environments and barn-derived substances present...
- The National Institute of Allergy and Infectious Diseases awarded University of California, Los Angeles $459,971 on August 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on mucosal IgA induction and spatiotemporal regulation of the microbiome. The research examines how immunoglobulin A antibodies produced in the intestine regulate the human gut microbiome in the absence of infection. The work investigates how IgA anchors bacterial...
- Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $5.18M to the University of California, San Diego under the Allergy and Infectious Diseases Research program (CFDA 93.855) on September 5, 2025, with completion scheduled for August 31, 2029. This research initiative investigates the relationship between skin microbiome composition and the development of allergic diseases, specifically atopic dermatitis (AD) and food allergy (FA),...
- The National Institute of Allergy and Infectious Diseases awarded New York University $1,694,434 on June 5, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on dietary and microbial strategies that suppress antibiotic-induced antimicrobial resistance in the gut microbiome. The project will systematically identify specific meals and dietary components that either alleviate or worsen antibiotic-induced microbiome damage, using advanced Bayesian...
- The National Institute of Allergy and Infectious Diseases awarded the Regents of the University of Michigan $598,906 on April 10, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate mechanisms of respiratory viral infections in hospitalized children. The research examines how early-life respiratory tract infections contribute to asthma development by analyzing nasal transcriptomes in children hospitalized with bronchiolitis or asthma. The project team...
- The National Institute of Allergy and Infectious Diseases awarded The Regents of the University of California, San Francisco $222,085 on October 24, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct research on skin microbiota-immune interactions that drive early life commensal tolerance. The research investigates how cutaneous immune cells maintain tolerance to skin commensal microbes while defending against pathogens, with focus on the role of CD301B+...
- The National Institute of Allergy and Infectious Diseases awarded The University Corporation $147,500 on September 1, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The recipient will conduct research to define the genomic and metabolic determinants by which select Akkermansia species and strains degrade non-fucosylated core human milk oligosaccharides (HMOs) during growth, and to identify ecological interactions among Akkermansia and other HMO-degrading bacteria...
The National Institute of Allergy and Infectious Diseases awarded The Regents of the University of California, San Francisco $825,786 on July 24, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate how diet-mediated gut microbiome interactions influence early-life susceptibility to respiratory infection and childhood asthma risk. The research project, titled "Determining Diet by Microbiome Interactions That Mitigate Early Life Susceptibility to Infection and Childhood Asthma Risk," uses prospective mother-infant dyad birth cohort data from the Binational Early Asthma and Microbiome Study (BEAMS) to examine the relationship between prenatal and infant dietary lipid profiles, microbial metabolite composition, and asthma-predictive symptom scores in infants of Mexican ancestry born in the United States versus counterparts in Mexico. The work identifies fecal lipid metabolites—including pro-inflammatory linoleic and palmitic acid derivatives and the asthma-predictive oxylipin 12,13-DHOME—as biomarkers differentially associated with infant respiratory symptom burden and infection risk, and aims to elucidate the mechanisms by which functionally distinct gut microbiomes metabolize dietary lipids to shape infant immune response. Work is performed in San Francisco, California. The award obligates $825,786 with an ultimate completion date of June 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $825.8k | 7/24/26 |