Project Grant R01AI201390
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh $799,572 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2031. This Project Grant funds time-resolved structural analyses of beta-lactam and beta-lactam inhibitor binding interactions with AmpC beta-lactamases, enzymes produced by gram-negative bacteria that confer resistance to commonly used...
- Federal Grant Award Summary The University of Pittsburgh received a $430,024 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 8, 2026, with a completion date of June 30, 2028. This research initiative investigates intestinal interactions between Clostridioides difficile and Clostridium perfringens type F, two major bacterial pathogens responsible for gastrointestinal disease...
- Federal Grant Award Summary The University of Pittsburgh received a $430,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 10, 2025, with completion scheduled for June 30, 2027. The project, titled "Training of Neutrophils to Defend Against a Lethal Bacterial Infection of the Lung," focuses on developing immunological strategies to enhance host defense against...
- Federal Grant Award Summary The University of Pittsburgh received a $641,889 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective April 1, 2026 through March 31, 2031. The award funds the development of a molecular taxonomy for immune-mediated diseases by combining expertise in immunogenetics, translational immunology, systems immunology, machine learning, and statistical genetics....
- Federal Grant Award Summary The University of Pittsburgh received a $437,250 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop and evaluate a rationally designed bacteriophage cocktail for treating multidrug-resistant (MDR) Pseudomonas aeruginosa infections. The award, obligated on February 4, 2026, with a completion date of January 31, 2028, funds research to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh a $447,783 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 11, 2025, to conduct preclinical research addressing prosthetic joint infection (PJI) pathophysiology to support clinical bacteriophage therapy development. The research will generate critical scientific knowledge on PJI mechanisms through three primary...
- Federal Grant Award Summary The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 25, 2025, with completion targeted for June 30, 2027. This award supports research targeting host nuclear receptors for the resolution of Methicillin-Resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs). The research aims...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh $718,028 on June 9, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support a five-year research initiative extending through May 31, 2031. This project grant funds fundamental research to decipher the gating mechanism of intraflagellar transport (IFT) in Trypanosoma brucei, a eukaryotic protozoan parasite responsible for...
- Federal Grant Award Summary The University of Pittsburgh received a $2,976,652 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2029. This award supports research investigating polyamine toxicity and resistance mechanisms in two epidemic bacterial skin pathogens: methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes...
- Federal Project Grant Award Summary The University of Pittsburgh received a $413,002 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on July 24, 2025, with a completion date of June 30, 2027. This award funds research to identify and characterize the protective role of interferon lambda (IFNL) in tuberculosis (TB) infection. The research aims to develop host-directed therapies...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Pittsburgh $633,470 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 9, 2026, for a five-year project extending through June 30, 2031. This project develops and evaluates enhanced primary care telemedicine capabilities for assessing acute respiratory tract infections (ARTIs) in young children, with particular emphasis on reducing unnecessary antibiotic prescribing. The initiative addresses the clinical challenge of diagnosing conditions requiring antibiotics—such as acute otitis media (AOM), acute bacterial sinusitis (ABS), and streptococcal pharyngitis—versus viral diagnoses where antibiotics are not indicated, through integration of commercially available home tele-otoscopes that enable primary care providers to conduct virtual examination of tympanic membranes during telemedicine visits. By combining timely telemedicine access with high-quality diagnostic capability, the project aims to advance dual public health and patient care objectives: reducing the estimated one-third to one-half of unnecessary antibiotics currently prescribed for ARTIs in young children (thereby mitigating antibiotic resistance and healthcare costs) while simultaneously meeting caregiver demand for prompt, same-day care outside traditional in-person pediatric office settings. The research leverages prior evidence demonstrating lower antibiotic prescribing rates in primary care telemedicine compared to non-pediatric urgent care and emergency department settings.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $633.5k | 7/9/26 |