Project Grant R01AI199482
- Federal Project Grant Award Summary The Johns Hopkins University received a $401,191 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective June 11, 2025 through May 31, 2027. This research initiative will characterize the neonatal nasal microbiome following parent-to-child nasal microbiota transplant (NMT) procedures conducted under FDA Investigational New Drug (IND) protocols....
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $4.34 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 13, 2025, with performance completion scheduled for May 31, 2030. This award funds a prospective cohort study examining the effects of vaccination on acute and post-acute respiratory viral infection (RVI) outcomes in solid organ transplant recipients...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $779,616 Project Grant effective April 10, 2026, through March 31, 2031, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This research initiative will characterize the defective human immunodeficiency virus type 1 (HIV-1) proviral reservoir in children and young adults living with perinatal HIV-1 infection. The project will determine the...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University $775,187 on August 1, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a five-year research project examining the impact of systemic immunosuppression on respiratory syncytial virus (RSV) antibody generation and effector functions following vaccination. The research will systematically study antibody responses to novel...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant totaling $427,313 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 20, 2026, with completion targeted for January 31, 2028. This research initiative investigates tertiary lymphoid structures in eosinophilic chronic rhinosinusitis with nasal polyps (ECRSWNP), a debilitating inflammatory condition affecting the...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $426,938 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 23, 2025, with a completion date of May 31, 2027. The award supports the development of a simplified, cost-effective mouse model of chronic Mycobacterium abscessus lung disease using BALB/c mice that requires only weekly cyclophosphamide administration. This...
- Federal Project Grant Award Summary National Jewish Health received a $776,394 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 19, 2026, with completion targeted for January 31, 2031. The grant supports investigator-initiated biomedical research examining prenatal programming of immune cells for tissue repair and remodeling in asthma, specifically investigating how...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $233,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 15, 2026, with completion scheduled for April 30, 2028. The research initiative, titled "Manipulation of Host Cell Peroxisomes by the Bacterial Pathogen Legionella," focuses on elucidating how the intracellular bacterial pathogen Legionella manipulates...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a $147,486 Project Grant effective September 21, 2025, through April 30, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated research aimed at identifying metabolic targets to reinvigorate exhausted CD8+ T cells, which become dysfunctional following prolonged antigen exposure and exhibit poor...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $414,368 to the University of California, Davis under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 23, 2025, with a completion date of June 30, 2027. This award funds research investigating the molecular mechanisms underlying persistent effects of early life exposure to aeroallergens and air pollution on lung function and remodeling. Using...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Johns Hopkins University a Project Grant of $822,060 (CFDA 93.855 – Allergy and Infectious Diseases Research) on May 11, 2026, to conduct research investigating the mechanisms by which prenatal maternal respiratory infection, particularly Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), shapes fetal lung epithelial immune memory and predisposes offspring to chronic inflammatory lung diseases such as asthma. Research will be performed in Baltimore, Maryland, through April 30, 2031. The project will deliver scientific research products examining how maternal viral infection during pregnancy creates epigenetic modifications in fetal lung epithelial cells through disruption of the stromal cell-derived factor 1/C-X-C chemokine receptor type 4 (SDF-1/CXCR4) signaling axis. Specifically, investigators will determine how infection timing affects immune memory formation, characterize mesenchymal-epithelial cell interactions in this process, and identify signaling pathways mediating epigenetic changes in inflammatory genes including Interleukin-33 (IL-33). Results are intended to uncover novel mechanisms of non-immune cell immune memory and inform development of preventive strategies for chronic inflammatory lung diseases in offspring exposed to maternal viral infections.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $822.1k | 5/12/26 |