Project Grant R01AI198609
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University Indianapolis a $435,875 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 1, 2026, with completion scheduled for June 30, 2028. This award funds research to identify intervention points within the cell-autonomous immune response to Chlamydia trachomatis infection that could promote bacterial clearance without broad-spectrum...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University Indianapolis a $790,946 Project Grant (CFDA 93.855: Allergy and Infectious Diseases Research) effective February 10, 2026, with a completion date of January 31, 2031. This research grant funds investigation into the dysregulation of humoral immunity following Plasmodium infection, specifically examining why malaria parasites fail to induce long-lasting protective antibody...
- Federal Project Grant Award Summary Indiana University Indianapolis received a $158,500 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded on April 10, 2026, with an ultimate completion date of March 31, 2028. The grant funds the development of a novel mouse model to analyze FOXP3+ Follicular Helper T (TFH) cells and their role in immune regulation. This research addresses a...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University Indianapolis a Project Grant of $816,699 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 9, 2026, with completion targeted for January 31, 2028. The research project investigates the molecular mechanisms driving reactivated toxoplasmosis in HIV/AIDS co-infected patients, with focus on understanding how latent Toxoplasma gondii parasites...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases awarded Indiana University Indianapolis a Project Grant of $781,241 on August 5, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a comprehensive systems analysis of anti-malarial monoclonal antibodies (mAbs) in clinical field trials. The primary deliverable is an integrated, multi-omics analytical investigation examining how innate immune signals influence the...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University Indianapolis a Project Grant of $700,209 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 12, 2026, with a completion date of April 30, 2031. This five-year research grant supports investigation into the impact of high-salt diet consumption on CD8 T cell immune responses during acute viral infection. The research will examine both...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University a $503,887 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop innovative therapeutic strategies targeting Vibrio bacterial infections. The award, dated September 1, 2025, with an ultimate completion date of August 31, 2026, funds research directed by co-principal investigators Dr. Jon Paczkowski and Dr. Julia Van Kessel to advance...
- Federal Grant Award Summary Indiana University Indianapolis has been awarded $435,875 under the National Institute of Allergy and Infectious Diseases (NIAID) Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a two-year project grant beginning April 3, 2026, and concluding March 31, 2028. The project, titled "Dissecting the Impact of Gut Evolution on Klebsiella Pneumoniae Pathogenesis," will deliver research services focused on understanding how bacterial...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Indiana University Indianapolis a $457,877 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 21, 2025, with an ultimate completion date of July 31, 2027. This award supports investigator-initiated research to identify and validate soluble lymphocyte activation gene-3 (sLAG-3) and insulin messenger RNA as potential biomarkers for early...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $1.595 million to Trustees of Indiana University on June 24, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project extending through May 31, 2030. The research addresses the structural basis of Human Immunodeficiency Virus-1 (HIV-1) Rev Response Element (RRE) and Rev Assembly, focusing on identifying alternative viral targets for drug development....
Indiana University Indianapolis received a $658,213 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2026 through June 30, 2031. This award supports research investigating how chronic viral infections, including HIV and hepatitis B and C, suppress dendritic cell (DC) function and consequently impair secondary immune responses. The research addresses a critical gap in understanding the mechanisms by which persistent viral infections diminish the generation of cytotoxic CD8 T cells and delay tumor clearance, with implications for improving immunotherapeutic interventions in patients with chronic viral infections. The project deliverables include scientific investigations examining the effects of sustained chronic inflammation on dendritic cell maturation and function, with the ultimate goal of identifying therapeutic targets to restore DC activation and enhance T cell responses during established infections. The research will produce peer-reviewed publications, novel mechanistic insights into virus-mediated immune dysfunction, and potentially translatable findings to inform vaccine and immunotherapy development strategies. By clarifying how chronic viral infections suppress antigen-presenting cell function—a conserved mechanism across multiple human pathogens—this funded research contributes to NIAID's broader mission of supporting innovative biomedical research addressing urgent infectious disease threats.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $658.2k | 6/30/26 |