Project Grant R01AI196738
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a $520,128 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) beginning August 1, 2025, with completion scheduled for July 31, 2030. This research initiative investigates molecular mechanisms by which Ehrlichia chaffeensis, the causative agent of human monocytotropic ehrlichiosis, manipulates host cell RNA...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $234,715 Project Grant on February 13, 2026, to The University of Texas Health Science Center at San Antonio under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports investigator-initiated research investigating the role of lymphotoxin beta receptor (LTBR) signaling in sensory neurons in the pathogenesis of Long COVID and testing the therapeutic...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $440,000 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Texas Medical Branch at Galveston for a two-year project period (August 1, 2025 – July 31, 2027). This Project Grant funds biomedical research investigating the pathogenic mechanisms of rickettsioses, devastating human infections that disproportionately affect microvascular...
- Federal Project Grant Award Summary Texas Tech University received a $150,220 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. The award supports research on sickle cell disease (SCD) severity prediction using magnetic susceptibility analysis and hemoglobin content measurement in blood cells. The research project aims to develop an early...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $440,000 in Project Grant funding under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Texas Medical Branch at Galveston, effective July 3, 2025, through June 30, 2027. This award supports research to determine the function and mechanism of long non-coding RNA CHAST in Trypanosoma cruzi infection and dissemination, which causes Chagas disease. The...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Utah $743,752 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to conduct a five-year investigator-initiated research project beginning August 1, 2025 and concluding July 31, 2030. This Project Grant supports fundamental biomedical research investigating the epigenetic mechanisms that govern CD4+ helper T cell dysfunction during chronic viral infections....
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Johns Hopkins University a $633,378 Project Grant on April 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate blood-brain barrier (BBB) integrity and immune dysfunction in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The research will compare neuropsychiatric and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases awarded a $440,000 Project Grant on July 17, 2025, to the University of Texas Medical Branch at Galveston under the Allergy and Infectious Diseases Research program (CFDA 93.855). This award supports research to characterize the role of tripartite motif (TRIM) proteins in regulating host innate immune responses against vector-borne bunyaviruses. The research utilizes Rift Valley Fever Virus and La Crosse...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $661,009 Project Grant to The University of Texas Southwestern Medical Center for a five-year research initiative (April 1, 2026 – March 31, 2031) under the Allergy and Infectious Diseases Research program (CFDA 93.855). This project delivers comprehensive genetic and immunological research investigating ABCF1 (ATP-binding cassette sub-family F member 1) variants in celiac disease and...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant of $576,501 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, with completion scheduled for July 31, 2030. This research project investigates the previously uncharacterized role of nucleoprotein (NP) exoribonuclease in Lassa virus (LASV) replication and fitness. The award...
Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Texas Tech University Health Sciences Center a $388,229 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective April 1, 2026, through March 31, 2031. This five-year research initiative investigates the relationship between endogenous retroviruses (ERVs) and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating condition characterized by persistent fatigue, post-exertional malaise, and cognitive impairment. The research employs advanced genomic methodologies, including RNA sequencing, whole-genome sequencing, and single-cell RNA sequencing analysis, along with the ERVcaller platform for precise ERV detection. The grant supports three primary research objectives: (1) identifying ERVs whose expression correlates with ME/CFS diagnosis and post-exertional malaise using RNA sequencing data from patient and control populations; (2) identifying ERV variants associated with ME/CFS susceptibility through whole-genome sequencing analysis; and (3) conducting additional genomic investigations to establish connections between ERV reactivation and ME/CFS pathology. By analyzing extensive datasets from ME/CFS patients and healthy controls, this represents the largest ERV study conducted in the ME/CFS population to date and aims to identify novel diagnostic biomarkers and therapeutic targets for this poorly understood chronic illness.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $388.2k | 4/1/26 |