Project Grant R01AI196092
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Sloan-Kettering Institute For Cancer Research a Project Grant totaling $3,519,992 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective March 1, 2026, with completion targeted for February 28, 2030. This grant supports the development of computational and microbiome-based clinical tools to predict, prevent, and mitigate gut-borne bloodstream infections in...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $3,178,476 to the Sloan-Kettering Institute for Cancer Research under the Allergy and Infectious Diseases Research program (CFDA 93.855) on January 28, 2026, for a project extending through December 31, 2029. The award supports investigator-initiated biomedical research focused on chalkophore-mediated respiratory oxidase flexibility and Mycobacterium tuberculosis virulence. The...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $489,500 to the Beckman Research Institute of the City of Hope under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 5, 2026, for a project period extending through January 31, 2028. The award supports fundamental research to elucidate the molecular mechanisms governing non-canonical microRNA-146a (mir-146a) biogenesis and its role in inflammatory...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $464,750 to Icahn School of Medicine at Mount Sinai on July 7, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project completion period extending through June 30, 2027. The award supports research focused on understanding and modulating T cell plasticity, specifically the transdifferentiation of TH17 cells into regulatory T cells...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Feinstein Institutes For Medical Research a Project Grant of $460,625 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 10, 2026, with a completion date of January 31, 2028. The award supports biomedical research focused on understanding the maturation and maintenance of the germinal center niche, specifically investigating follicular dendritic cells...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Sloan-Kettering Institute for Cancer Research a $3.52 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for research on chromatin architecture regulating trained immunity in antiviral natural killer (NK) cells. The award, obligated on July 25, 2025, funds a four-year research initiative extending through June 30, 2029, investigating how...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $899,850 to the Whitehead Institute for Biomedical Research under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 20, 2026, for a project extending through January 31, 2031. This Project Grant supports biomedical research investigating how apicomplexan parasites recognize and invade host cells—a critical mechanism for understanding parasitic infections that...
- Federal Project Grant Award Summary New York University School of Medicine received a $755,801 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 3, 2026, with completion targeted for January 31, 2031. The research project investigates the regulatory mechanisms controlling CD4+ and CD8+ T cell function through examination of the CLNS1A protein, a molecule critical to T...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $890,877 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the La Jolla Institute for Immunology, effective February 1, 2026, through January 31, 2031. This award funds basic immunological research aimed at elucidating the structural and functional mechanisms of Interleukin-1 Receptor 8 (IL-1R8), a critical immunoregulatory protein that...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $3,066,524 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the Sloan-Kettering Institute for Cancer Research on August 21, 2025, with a completion date of July 31, 2029. This Project Grant funds research into the cell death machinery underlying VEXAS (Vacuoles, E1-Ubiquitin-Activating Enzyme, X-Linked, Autoinflammatory, Somatic), a somatic autoinflammatory...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded $616,042 to the Sloan-Kettering Institute for Cancer Research under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 3, 2026, for a project period extending through January 31, 2031. The award supports investigator-initiated research aimed at decoding the role of AIRE-expressing THETIS cells in peripheral self-tolerance, with research activities conducted at the awardee's facility in New York, NY. This project delivers fundamental immunological research focused on understanding how self-reactive T cells are restrained in peripheral tissues following escape from thymic deletion. The research investigates whether AIRE+ THETIS cells (antigen-presenting cells recently identified by the research team) regulate peripheral tolerance to self-antigens through expression of tissue-restricted self-antigens and immune-regulatory molecules, utilizing parallel analyses between AIRE+ THETIS cells and AIRE+ medullary thymic epithelial cells. The deliverables include novel scientific findings on extra-thymic immune tolerance mechanisms, characterization of molecular pathways governing AIRE-dependent immune regulation, and advancement of knowledge relevant to preventing destructive autoimmune inflammation—outcomes consistent with NIAID's mission to support biomedical research addressing immunologic diseases.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $616.0k | 2/3/26 |