Project Grant R01AI195888
- Federal Grant Award Summary The University of Texas Medical Branch at Galveston received a $440,000 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025 through June 30, 2027. This award supports research to develop and optimize a deep learning artificial intelligence model, designated SDAP_AI (Structural Database of Allergenic Proteins – Artificial Intelligence),...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $250,000 Project Grant to the Regents of the University of Michigan on August 21, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award funds research to develop diagnostic and prognostic tools for distinguishing the heterogeneity of allergic responses in food allergy patients. The research employs a novel synthetic immunological niche scaffold technology to...
- Federal Project Grant Award Summary Northwestern University's Sponsored Research Division received a $106,922 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 26, 2026, with a completion date of October 31, 2028. The award supports biomedical research investigating the mechanisms of food allergen absorption and anaphylaxis, with emphasis on identifying the role...
- Federal Grant Award Summary The University of Texas Southwestern Medical Center received a $392,000 Project Grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), awarded August 1, 2025, with a completion date of July 31, 2028. Under the direction of Principal Investigator Dr. Jeff Sorelle, the project will investigate immunoglobulin E (IgE) glycosylation as a potential...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts General Hospital $806,466 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a five-year project period from August 1, 2025 through July 31, 2030. This Project Grant supports research to define protective immunoglobulin G (IgG) antibody signatures associated with successful peanut oral immunotherapy (OIT) outcomes. The research addresses a critical gap...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The University of Texas Health Science Center at San Antonio $116,022 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 20, 2025, for a project period concluding November 30, 2025. The award supports research into the SARS-CoV-2 main protease (Mpro) dimerization mechanism, a critical enzyme that enables viral replication and pathogenesis. The funded research will...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $528,157 to The University of Texas MD Anderson Cancer Center for a five-year project period (September 1, 2025 through August 31, 2030) under the Allergy and Infectious Diseases Research program (CFDA 93.855). This project grant supports the development and application of a deep learning foundation model called PMTNet-Omni to advance T cell receptor (TCR)-antigen interaction...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant of $576,501 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, with completion scheduled for July 31, 2030. This research project investigates the previously uncharacterized role of nucleoprotein (NP) exoribonuclease in Lassa virus (LASV) replication and fitness. The award...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Maryland, Baltimore $466,500 in Project Grant funding under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 1, 2026, with a completion date of January 31, 2031. This award supports a five-year research initiative investigating the relationship between gut microbial protein metabolism and response to peanut oral immunotherapy (POIT) in...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $5.18 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of California, San Diego, effective September 5, 2025, through August 31, 2029. This research project investigates the relationship between skin microbiota colonization patterns and the development of allergic diseases, specifically atopic dermatitis (AD) and food allergy...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a Project Grant of $429,499 under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 13, 2026, through January 31, 2031. This award funds the development and validation of AllergenAI, a novel machine learning tool designed to distinguish allergenic from non-allergenic proteins and identify potential cross-reactive allergens. The primary deliverables include: (1) enhancement of the existing machine learning model by incorporating three-dimensional structural information generated through AlphaFold-2 protein modeling across three allergen protein databases (SDAP 2.0, COMPARE, and ALGPRED); and (2) experimental validation of the improved model's predictive accuracy using well-characterized vicilin allergen family proteins, including peanut allergen ARA H 1 and homologues found in tree nuts, legumes, and cotton. This research addresses a significant public health gap by developing computational tools to identify allergenic proteins and predict cross-reactivity patterns among the vast catalog of proteins in current proteome databases. The outcome will support food safety manufacturers, clinical diagnosis, and allergen management in elimination diets, thereby reducing the burden on patients, families, and healthcare systems affected by the rising prevalence of food allergies in developed nations.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $429.5k | 2/13/26 |