Project Grant R01AI195745
- Federal Grant Award Summary Dartmouth College, through its Office of Sponsored Projects, received a Project Grant award of $105,076 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award was obligated on December 20, 2025, with a completion date of July 31, 2027, and supports research to be conducted in New Hampshire. The grant funds basic biomedical research investigating the dual functionality...
- Federal Project Grant Award Summary Award Details: Dartmouth College received a $630,677 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The award, obligated on February 2, 2026, supports a five-year research project extending through January 31, 2031, with performance conducted at the Hanover, New Hampshire campus. Research Products and Services: The grant funds biomedical research...
- Federal Grant Award Summary Trustees of Dartmouth College received a $246,562 Project Grant from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded June 6, 2025, with completion scheduled for February 28, 2027. The research project, conducted at Dartmouth's Hanover, New Hampshire facilities, focuses on understanding how hypoxia-associated morphological variations in Aspergillus fumigatus (AF)—a common...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Dartmouth-Hitchcock Clinic a Project Grant totaling $232,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective February 9, 2026, with a completion date of January 31, 2028. The project, titled "Multiplexed Reporter Platforms for Probing the Bile Acid-Nuclear Receptor Interactome," involves the development and deployment of innovative multiplex nuclear...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a $450,630 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a two-year project period from August 1, 2025, through July 31, 2027. The award funds spatiotemporal investigation of interactions between pneumolysin, pulmonary epithelium, and polymorphonuclear leucocytes (PMNs/neutrophils) that contribute to...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Boston Children's Hospital $151,040 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on December 4, 2025, to support a project extending through July 31, 2028. This Project Grant funds basic science research investigating the regulatory mechanisms of a small regulatory RNA (sRNA) designated BECO in Pseudomonas aeruginosa, a gram-negative bacterium that causes serious...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Tufts University School of Medicine a Project Grant totaling $3,178,626 under the Allergy and Infectious Diseases Research program (CFDA 93.855) for the period August 26, 2025 through July 31, 2029. This award supports research investigating Yersinia pseudotuberculosis (YPTB) Type 3 Secretion System (T3SS) effector protein activities in M cells during murine infection. The research...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $151,808 to the University of Colorado-Denver under the Allergy and Infectious Diseases Research program (CFDA 93.855) on May 14, 2025, with a completion date of November 30, 2026. This Project Grant funds investigator-initiated research examining the role of the Group B Streptococcus (GBS) Type VII Secretion System (T7SS) in polymicrobial environments. The research addresses the...
- Federal Project Grant Award Summary Tufts University School of Medicine received a $453,750 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. The grant funds research to investigate mechanisms by which bacteriophages evade cyclic oligonucleotide-based antiviral defense systems in bacteria, with specific focus on how phage proteins antagonize...
- Federal Project Grant Award Summary Tufts University School of Medicine received a $647,187 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 3, 2025, with a completion date of June 30, 2030. The award supports biomedical research investigating the novel role of heme synthesis in controlling regulatory T cell (Treg) fitness and function. The research focuses on...
Award Details: The National Institute of Allergy and Infectious Diseases (NIAID) awarded Dartmouth College a Project Grant totaling $825,054 under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of February 13, 2026 and completion date of January 31, 2031. Research Deliverables: This project will advance scientific understanding of how Type VI Secretion System (T6SS) immunity proteins influence airway microbiota composition and pathogen fitness, with particular focus on Pseudomonas aeruginosa infections in cystic fibrosis patients. The research will investigate the dual functionality of the TSIT (T6SS immunity protein), which serves both as a bacterial immunity mechanism and as a transcriptional regulator affecting biofilm formation, thereby elucidating microbial ecology and interspecies interactions in the respiratory tract. Deliverables will include fundamental research findings on T6SS effector mechanisms, characterization of TSIT homologs in gram-negative organisms, and insights into how these bacterial defense systems influence polymicrobial community dynamics—knowledge with potential applications for understanding chronic infection establishment and informing therapeutic strategies for cystic fibrosis-related airway disease.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $825.1k | 2/13/26 |