Project Grant R01AI194375
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,041,944 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Rutgers, The State University of New Jersey. The grant will support research to understand the mechanisms underlying heterogeneous transmission of Mycobacterium tuberculosis (MTB) strains, as well as the immune responses of individuals who resist MTB infection despite exposure. The research aims to identify potential...
- The U.S. National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,166,933 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Vanderbilt University Medical Center to study Mycobacterium tuberculosis transmission. The project aims to identify bacterial genetic and phenotypic features associated with M. tuberculosis transmission outcomes, including infection, subclinical TB, and clinical TB disease. It will also define M. tuberculosis...
- This federal Project Grant award of $1,141,359 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to investigate the mechanisms underlying tuberculosis (TB) transmission, with a focus on understanding how host and bacterial factors influence the cough reflex and aerosolization of Mycobacterium tuberculosis (MTB). The project aims to analyze the impact of biological...
- This Project Grant award of $375,996.00 from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), supports research to assess the potential carriage state of Mycobacterium tuberculosis (MTB) in the upper respiratory tract of individuals who have been exposed to tuberculosis (TB) but do not display active disease. The research aims to understand the mechanisms by which the majority of people...
- This $1,173,748.00 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research on the role of asymptomatic tuberculosis (TB) in disease transmission. The research aims to improve understanding of when individuals become infectious and where transmission is occurring, particularly in community settings outside of household contacts. Key areas of focus include characterizing...
- This $781,369 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program. The funding supports research to investigate the role of B cells in regulating lung inflammation and disease progression in chronic tuberculosis (TB). The research aims to elucidate how B cells drive CD4+ T cell expansion and pro-inflammatory responses, as well as how B cells may restrict...
- The federal Project Grant award of $3,089,360 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports the development and evaluation of innovative tuberculosis (TB) diagnostic platforms and assays. The 5-year project, awarded to Rutgers, The State University of New Jersey, aims to accelerate promising TB diagnostics through a fast-paced pipeline that includes technology scouting, development...
- This $854,000 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to assess post-tuberculosis (TB) lung disease in TB patients with and without HIV coinfection. The project will utilize novel positron emission tomography (PET) imaging techniques, such as 11C-rifampin PET, to longitudinally profile lesional characteristics and antibiotic exposures in animal models...
- This Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID, CFDA 93.855 Allergy and Infectious Diseases Research), provides $466,500.00 in funding to the University of North Carolina at Chapel Hill (UNC-CH) to conduct research on the bacterial genetic basis underlying the transmissibility of tuberculosis (TB). The project aims to: (1) identify key mutations that drive high transmissibility in Mycobacterium tuberculosis (MTB) using a global collection of...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), Catalog of Federal Domestic Assistance (CFDA) 93.855 Allergy and Infectious Diseases Research program, aims to inform the development of a simple, highly sensitive and specific, non-sputum-based point-of-care test (POCT) for tuberculosis (TB) diagnosis. The $850,711 award to Albert Einstein College of Medicine, located in Bronx, NY, will support the investigation of a panel of six monoclonal...
This Project Grant award, titled "Transmission Links and Clinical Spectrum of Exhaled Mycobacterium Tuberculosis", is funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The $1,032,233 grant aims to investigate the role of sputum-negative, Mycobacterium tuberculosis (MTB) breath-positive individuals in disease transmission and characterize their underlying clinical spectrum. The study will use breath sampling techniques, MTB viability assays, and longitudinal clinical evaluations to assess the prevalence of sputum-negative individuals shedding viable MTB in their breath across high and low TB burden settings, as well as examine how sputum-negative exhaled MTB reflects underlying pathology, immune activation, and disease progression over time. The award was made to Rutgers, The State University of New Jersey, a prominent public research university, and has a performance period from September 10, 2025 to August 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 9/10/25 |