Project Grant R01AI190417
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University $222,098 through the Allergy and Infectious Diseases Research program (CFDA 93.855) on July 3, 2025, for a project titled "Role of the Septin Cytoskeleton in Plasma Membrane Repair." The project, extending through January 31, 2027, focuses on fundamental research to elucidate the mechanisms by which septin cytoskeletal proteins facilitate plasma...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a $433,125 Project Grant on July 2, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the molecular mechanisms by which influenza A virus (IAV) protein PB1-F2 induces acute respiratory distress syndrome (ARDS). The research will examine how PB1-F2 interacts with mitochondrial antiviral-signaling protein (MAVS) to impair...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases awarded The Ohio State University a $537,861 Project Grant (CFDA 93.855 – Allergy and Infectious Diseases Research) effective August 1, 2025, through July 31, 2030, to develop advanced statistical methods for studying infectious disease transmission and control. The grant supports the extension of pairwise survival analysis methodologies through three primary objectives: (1) developing efficient...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a $433,125 Project Grant effective August 21, 2025, through July 31, 2027, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This exploratory research initiative focuses on enhancing antibody-dependent cellular cytotoxicity (ADCC) in HIV vaccine development through application of a novel oral adjuvant. The research builds upon the RV144...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $527,960 to the Research Institute at Nationwide Children's Hospital on August 18, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project extending through July 31, 2030. The research investigates the role of glutathione reductase (GSR) in regulating cell metabolism and signaling during neutrophil-pathogen interactions, specifically examining how GSR...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a Project Grant of $605,778 on July 7, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to investigate the role of ARIADNE RBR E3 ubiquitin protein ligase 2 (ARIH2) in influenza A virus (IAV) replication and pathogenesis within airway epithelial cells. The research will be conducted at The Ohio State University's Columbus, Ohio location...
- Federal Project Grant Award Summary The Ohio State University received a $249,000 Project Grant award dated August 22, 2025, under the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) to investigate the role of host messenger ribonucleic acid (mRNA) cleavage by ribonuclease L (RNase L) in viral infections. The research will be conducted at the university's Columbus, Ohio location and extends through July 31, 2028. The...
- Federal Project Grant Award Summary The Ohio State University College of Medicine received a $209,122 Project Grant award from the National Institute of Allergy and Infectious Diseases under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective May 1, 2025, through April 30, 2030. The grant funds the SHORT-TERM RESEARCH IN IMMUNOLOGY AND VIROLOGY EXPERIENCE (STRIVE) T35 training program, which delivers a 12-week summer research experience for medical students between...
- Federal Grant Award Summary Georgetown University received a $429,000 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective July 1, 2025, through June 30, 2027. The project involves conducting basic and translational research to evaluate cell-type-specific injury markers in liver allografts during normothermic machine perfusion (NMP). The research aims to develop novel viability...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded The Ohio State University a $597,573 Project Grant on June 1, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct structural and dynamic studies of protein and protein-nucleic acid assemblies relevant to human health and disease. The research employs advanced spectroscopic and microscopic techniques, including multidimensional magic-angle spinning solid-state...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Ohio State University a Project Grant valued at $758,645 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 2, 2026, with a completion date of January 31, 2031. This research initiative focuses on investigating the mechanisms by which the liver clears lipopolysaccharide (LPS), a potent bacterial endotoxin, from blood circulation—a critical process in host defense against endotoxemia. The project will advance understanding of how liver sinusoidal endothelial cells eliminate circulating LPS through stabilin receptor-mediated endocytosis and identify novel serum and intracellular proteins that facilitate this clearance process. The research deliverables include scientific findings on the role of stabilin-1 and stabilin-2 receptors in rapid LPS clearance, characterization of the inflammatory response mechanisms in hepatic cells, and identification of molecular facilitators of LPS uptake and degradation through liquid chromatography-tandem mass spectrometry analysis. These research outputs are intended to provide critical insights for developing therapeutic interventions for endotoxemia and related LPS-associated diseases affecting multiple organ systems. The project will be conducted at The Ohio State University's Office of Sponsored Programs in Columbus, Ohio.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $758.6k | 2/2/26 |