Project Grant R01AI190369
- Federal Grant Award Summary Harvard Medical School received a $169,043 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 15, 2025, with completion targeted for February 29, 2028. The award supports fundamental biomedical research investigating the molecular mechanisms of gasdermin D (GSDMD) pore formation and membrane rupture in pyroptotic cell death pathways. The research...
- Federal Grant Award Summary Award Details: The National Institute of Allergy and Infectious Diseases (NIAID) awarded President and Fellows of Harvard College (operating as Harvard Medical School) $253,500 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 13, 2025, with a completion date of July 31, 2027. Research Scope: This Project Grant supports research examining the mechanisms of infection and transduction by a novel Herpes Simplex Virus 1 (HSV-1) gene...
- Federal Project Grant Summary Harvard Medical School, operating through the President and Fellows of Harvard College, received a $835,269 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), with an award date of February 6, 2026, and a completion date of January 31, 2031. The research conducted at the Boston, MA facility focuses on deciphering cytokine regulation of lymphocyte trafficking...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $414,029 to Harvard College's Office for Sponsored Programs on February 19, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support a five-year research project through January 31, 2031. This project grant funds fundamental research aimed at understanding programmed ribosomal frameshifting in coronaviruses, a critical viral mechanism that allows...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $160,448 to Harvard Medical School through the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 28, 2026, to support a postdoctoral fellowship project investigating factors involved in assembly of the mycolata envelope in bacteria. The award will support research through January 1, 2029, and focuses on elucidating the role of the TMAT-AFTD (mycolic acid...
- Summary of Federal Project Grant Award Harvard Medical School received a $168,219 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded May 19, 2025, with a completion date of December 31, 2026. The grant funds basic immunological research investigating the regulation of the inflammasome—a critical component of the innate immune system—specifically examining the role of a novel...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $325,806 to Harvard Medical School (President and Fellows of Harvard College) on September 19, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to support the Bacteriology PhD Training Program (GPIB). This training grant provides stipend support and associated educational resources for eight second- and third-year graduate students conducting bacteriology...
- Federal Grant Award Summary Harvard Medical School received a $125,901 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective September 3, 2025, with completion targeted for August 31, 2027. The grant supports investigator-initiated research focused on elucidating the mycomembrane protein assembly pathway in Mycobacteriales species, with emphasis on understanding how mycolate...
- Federal Grant Award Summary DISCOVERY OF ANTIMICROBIAL METABOLITES FROM THE HUMAN GUT MICROBIOTA USING HIGH-THROUGHPUT SCREENING The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $463,375 to the President and Fellows of Harvard College on February 2, 2026, under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research, conducted at Harvard's Cambridge, Massachusetts facility with a completion date of January 31, 2028, focuses...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Brigham & Women's Hospital a $170,411 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 8, 2025, with a completion date of July 31, 2030. The award supports a mentorship and training initiative focused on developing the next generation of patient-oriented translational virologists and physician scientists. The primary deliverables include...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded Harvard College $916,436 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop human thymus engineering technologies for immunotherapy applications. The award, effective February 5, 2026, through January 31, 2031, supports research focused on generating functional, antigen-specific T cells derived from induced pluripotent stem cells (iPSCs) by replicating the native thymic microenvironment. The project addresses critical gaps in current iPSC-derived T cell production, which currently yields suboptimal results compared to T cells naturally educated in the thymus, by investigating biomaterial scaffolds that mimic thymic niches and support appropriate spatial-temporal cell organization, including the critical cortical and medullary zone trafficking dynamics essential for proper T cell education. The research deliverables will advance immunotherapies for disease treatment, particularly cancer, by scaling production of customized human T cells from patient-derived iPSCs. The work will generate knowledge and potentially prototype biomaterial systems that combine iPSC-derived progenitors with engineered extracellular matrix components that replicate thymic tissue sub-architecture, addressing the unmet need for reproducible in vitro thymic development. This project is conducted at Harvard's Cambridge, Massachusetts campus under the Office for Sponsored Programs Division, leveraging the institution's established expertise in biomedical research and stem cell development to support national priorities in regenerative medicine and advanced immunotherapies.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $916.4k | 2/5/26 |