Project Grant R01AI187574
Award Date 9/1/25
Completion Date 8/31/30
Dollars Obligated $612K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Virginia, USA
Similar Awards
- This federal Project Grant award for $329,039, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to determine the genetic relatedness, effective population size, and local adaptation of invasive Aedes aegypti mosquito populations. The award aims to advance understanding of how evolutionary forces shape the dispersal and population dynamics of this mosquito species, which can transmit...
- This $157,884 Project Grant, awarded on December 26, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate the effects of a chromosomal inversion in the Anopheles coluzzii mosquito on gene regulation and its relationship to malaria resistance. The central hypothesis is that genetic variation between the inversion forms leads to differential enhancer activity and gene...
- This Project Grant award of $2,536,503 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to understand how the ability of Aedes aegypti mosquitoes to tolerate desiccation affects their potential as disease vectors. The research aims to identify genetic mechanisms linking desiccation tolerance to susceptibility to Zika, Chikungunya, and Dengue viruses in the mosquito midgut. Key...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $302,537 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Synvect, Inc. to finalize the development and commercialization of their NextGenSIT technology for Aedes aegypti mosquito control. The objectives of this grant are to: 1) finalize the genetic components for producing competitive, sterile male Ae. aegypti mosquitoes using CRISPR gene knockouts; 2) develop and validate...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), is funding research to develop new tools and technologies for vector control of the Aedes aegypti mosquito, an important disease vector. The key focus is on evaluating conditional and sex-specific lethal systems that can restrict lethal transgene expression and reduce the fitness load on mosquito populations, as...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $441,502 to the University of Texas Health Science Center at Houston (UTHealth) to advance CRISPR-based genome editing strategies for managing Aedes aegypti mosquito populations. The key objectives are to: 1) design a CAS12 temperature-dependent system that requires only one strain to produce sterile male...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $423,125 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Texas A&M University System Health Science Center. The grant, awarded on July 17, 2025, aims to develop an intein-based QF2 system for controllable protein expression in the nervous system of the Aedes aegypti mosquito. This research seeks to leverage genetic and synthetic biology tools to disrupt the propagation of...
- The federal Project Grant award titled "MOVING TOWARD TARGETED ARBOVIRUS CONTROL: USING THE VIROME TO DETERMINE AEDES DISPERSAL AND POPULATION STRUCTURE" was provided by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) in the amount of $247,362.00. The award, with a performance period from September 8, 2025 to August 31, 2027, will be used by Cornell University to leverage genetic variation in insect-specific viruses...
- The University of Washington received a $458,849 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to conduct research aimed at uncovering the sensory mechanisms mosquitoes use to detect blood. The project seeks to leverage emerging single-cell RNA sequencing and high-throughput genetic analysis approaches to deeply characterize the diversity of sensory neurons in the mosquito labrum (feeding structure) and...
- This Project Grant award of $211,038 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research at The Johns Hopkins University to investigate a new strategy for controlling mosquito populations. The key focus is on targeting the enzyme iodotyrosine deiodinase, which plays a critical role in protecting insects like fruit flies from the accumulation of harmful halotyrosines that can suppress...