Project Grant R01AI184979
- This $570,760 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports a multidisciplinary research project to study the structure and function of intraflagellar transport (IFT) in the trypanosomatid parasite Leishmania, which causes several major human diseases. The research aims to elucidate the conserved and parasite-specific features of Leishmania...
- This $147,656 federal Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to understand the role of transmembrane proteins in the cell division process of the malaria parasite Plasmodium falciparum. The award, effective January 22, 2025 through October 31, 2027, will enable the integration of biochemical and super-resolution microscopy approaches to decipher...
- This $501,800 Project Grant was awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), to The Children's Hospital Corporation (doing business as Boston Children's Hospital) on August 4, 2025. The grant supports research to use cryo-electron tomography to gain new molecular insights into the divergent cell division process of the Plasmodium falciparum parasite, which causes malaria. The research...
- This $516,175 Project Grant was awarded on June 23, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant was awarded to Seattle Children's Hospital, doing business as Seattle Children's Research Institute, to evaluate the impact of pre-existing humoral immunity on hepatocyte death in the context of malaria. The research aims to explore how pre-existing immunity to malaria may...
- This Project Grant award of $430,251 from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) aims to support fine-resolution genetic mapping of advanced intercross lines of the snail vector Biomphalaria glabrata. The goal is to identify the genomic regions and genes that control the shedding of cercariae, the infectious stage of the Schistosoma mansoni parasite that causes schistosomiasis. The researchers at the University of New...
- This $1,174,636 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) supports the development of next-generation ELQ compounds for the treatment and prevention of malaria. The research aims to identify novel, rapidly acting anti-malarial drugs to target the blood and liver stages of the Plasmodium falciparum parasite, as well as formulations suitable for long-acting...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $806,208 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to Weill Medical College of Cornell University. The project, titled "Spatial Omics to Understanding HBV Control in People with HIV Coinfection," will leverage cutting-edge spatial proteomic and transcriptomic technologies to analyze the impact of HIV-related immune suppression and restoration on the...
- This federal Project Grant award of $426,938, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to explore the combined use of human anti-RH5 monoclonal antibodies and small molecule inhibitors against asexual Plasmodium falciparum malaria parasites. The research aims to assess the potential for additive, synergistic, or antagonistic effects of these combined interventions in...
- This $423,500 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) supports research to examine the role of invariant natural killer T (iNKT) cells in driving pathogenic T cell responses in experimental cerebral malaria. The research aims to determine how the T cell receptor (TCR) mechanosensing properties of iNKT cells shape the development of CD8 T cell-mediated pathology in Plasmodium infection. The grant...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $777,360 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Washington University to advance research on lymphatic filariasis (LF) elimination. The project aims to leverage genomic epidemiology to monitor the number of reproductively active adult parasites, differentiate new and established maternal parasite lineages, and understand the drivers of LF resurgence in areas that...
This $578,027 federal Project Grant was awarded on September 25, 2025 by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant will fund a randomized controlled trial (RCT) to evaluate varying frequencies of praziquantel (PZQ) treatment to reverse or halt hepatic fibrosis in 600 subjects aged 15-40 in Lake Albert, Uganda. The project aims to identify approaches that best reverse or halt schistosomiasis-related fibrosis, as well as develop novel biomarkers to predict fibrosis progression. The awardee is Rhode Island Hospital, a division of Lifespan Corporation, an academic medical center in Providence, RI. The project will be conducted at the awardee's facilities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $249.8k | 9/25/25 | ||
| Not listed | $328.3k | 9/24/25 |