Project Grant R01AI183979
- This $190,892 Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) will support a study to optimize tuberculosis (TB) active case finding strategies in Nairobi, Kenya. The key products and services to be delivered include: Employing multiple data sources on human mobility and activity spaces to identify high-yield geographic locations for TB screening within Nairobi. Developing a geospatial model to estimate...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $301,826 Project Grant on August 20, 2025 to the University of Washington to develop novel agents to eliminate tuberculosis (TB) persisters. The grant, under CFDA 93.855 - Allergy and Infectious Diseases Research, aims to assess the potential of the FDA-approved drug netupitant (NTP) as an anti-persister agent for TB treatment. The University of Washington will use molecular genetic and biochemical strategies to define...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $536,148 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Tufts University School of Medicine to conduct research on integrating point-of-care urine isoniazid testing into routine tuberculosis (TB) care in India. The research aims to facilitate early and accurate identification of TB patients who are at risk of poor outcomes, including death and disease recurrence, due to...
- The University of Washington received a $188,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The grant supports research to investigate the role of the lung inflammatory environment and cellular milieu in controlling Mycobacterium tuberculosis (MTB) infection and preventing tuberculosis (TB) disease. Specifically, the research will test the hypothesis that interferon gamma-activated...
- This $854,000 Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research Federal Grant Program (CFDA 93.855), aims to assess post-tuberculosis (TB) lung disease in TB patients with and without HIV coinfection. The project will utilize novel positron emission tomography (PET) imaging techniques, such as 11C-rifampin PET, to longitudinally profile lesional characteristics and antibiotic exposures in animal models...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $4,760,584 Project Grant under the Allergy and Infectious Diseases Research (CFDA 93.855) federal grant program to the Regents of the University of California, San Francisco (UCSF) for the "RAPID RESEARCH FOR DIAGNOSTICS DEVELOPMENT IN TB NETWORK: EPISODE 2 (R2D2 TB NETWORK II)" project. The goal of this project is to address the critical unmet need for better tuberculosis (TB) diagnostics in high-burden...
- This $1,450,790 Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research grant program (CFDA 93.855), is for the "RE-EVALUATING THE DURATION IN CHILDREN OF TB TREATMENT (REDUCE TB): A PHASE 2 DURATION RANDOMIZED TRIAL" project. The project aims to address the significant public health challenge of tuberculosis (TB) in children, with approximately 1.3 million new cases reported globally in...
- This $1,173,748.00 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will fund research on the role of asymptomatic tuberculosis (TB) in disease transmission. The research aims to improve understanding of when individuals become infectious and where transmission is occurring, particularly in community settings outside of household contacts. Key areas of focus include characterizing...
- The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,136,143 Project Grant under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855) to study post-tuberculosis lung disease (PTLD) in youth with and without HIV globally. The project will leverage the Tuberculosis Sentinel Research Network (TB-SRN) in 11 countries to establish the prevalence of PTLD in youth, identify modifiable risk factors, and assess the impact on quality of life....
- The U.S. National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,166,933 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Vanderbilt University Medical Center to study Mycobacterium tuberculosis transmission. The project aims to identify bacterial genetic and phenotypic features associated with M. tuberculosis transmission outcomes, including infection, subclinical TB, and clinical TB disease. It will also define M. tuberculosis...
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $690,538 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to the University of Washington for the project "EXPANDING ACCESS AND IMPACT OF TUBERCULOSIS PREVENTIVE THERAPY: COMMUNITY-FRIENDLY DELIVERY AND MONITORING OF TPT TO IMPROVE UPTAKE AND REDUCE TB TRANSMISSION." The project aims to explore new, person-friendly models of tuberculosis preventive therapy (TPT) delivery to increase uptake, adherence, and completion of TPT, especially among people living with HIV and other high-risk populations in Kenya. The award period runs from August 19, 2025 to July 31, 2030. The project builds on successful models of differentiated HIV care delivery to adapt community-based and multi-month TPT dispensing approaches, leveraging the availability of shorter, safer TPT regimens.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $690.5k | 8/19/25 |